inclusion criteria: 1. participants must have read, understood, and signed the informed consent form (icf). 2. participants of either gender aged 12 years and older at screening. 3. medically stable 4. must be able to attend all visits of the study and comply with all study procedures, 5. women of childbearing potential (wocbp) must be able and willing to use at least 1 highly effective method of contraception for a minimum of 3 months after the last dose of study vaccine. 6. wocbps must have a negative pregnancy test prior to each vaccination.

inclusion criteria: 1. participants must have read, understood, and signed the informed consent form (icf). 2. participants of either gender aged 12 years and older at screening. 3. medically stable 4. must be able to attend all visits of the study and comply with all study procedures, 5. women of childbearing potential (wocbp) must be able and willing to use at least 1 highly effective method of contraception for a minimum of 3 months after the last dose of study vaccine. 6. wocbps must have a negative pregnancy test prior to each vaccination.

inclusion criteria: participants must have read, understood, and signed the informed consent form (icf). participants of either gender aged 12 years and older at screening. medically stable must be able to attend all visits of the study and comply with all study procedures, women of childbearing potential (wocbp) must be able and willing to use at least 1 highly effective method of contraception for a minimum of 3 months after the last dose of study vaccine. wocbps must have a negative pregnancy test prior to each vaccination.

inclusion criteria: participants must have read, understood, and signed the informed consent form (icf). participants of either gender aged 12 years and older at screening. medically stable must be able to attend all visits of the study and comply with all study procedures, women of childbearing potential (wocbp) must be able and willing to use at least 1 highly effective method of contraception for a minimum of 3 months after the last dose of study vaccine. wocbps must have a negative pregnancy test prior to each vaccination.

inclusion criteria: 1. participants must have read, understood, and signed the informed consent form (icf). 2. participants of either gender aged 12 years and older at screening. 3. medically stable 4. must be able to attend all visits of the study and comply with all study procedures, 5. women of childbearing potential (wocbp) must be able and willing to use at least 1 highly effective method of contraception for a minimum of 3 months after the last dose of study vaccine. 6. wocbps must have a negative pregnancy test prior to each vaccination.

inclusion criteria: 1. participants must have read, understood, and signed the informed consent form (icf). 2. participants of either gender aged 12 years and older at screening. 3. medically stable 4. must be able to attend all visits of the study and comply with all study procedures, 5. women of childbearing potential (wocbp) must be able and willing to use at least 1 highly effective method of contraception for a minimum of 3 months after the last dose of study vaccine. 6. wocbps must have a negative pregnancy test prior to each vaccination.

inclusion criteria: 1. participants must have read, understood, and signed the informed consent form (icf). 2. participants of either gender aged 18 years and older at screening. 3. medically stable 4. must be able to attend all visits of the study and comply with all study procedures, 5. women of childbearing potential (wocbp) must be able and willing to use at least 1 highly effective method of contraception for a minimum of 3 months after the last dose of study vaccine. 6. wocbps must have a negative pregnancy test prior to each vaccination.

inclusion criteria: 1. participants must have read, understood, and signed the informed consent form (icf). 2. participants of either gender aged 18 years and older at screening. 3. medically stable 4. must be able to attend all visits of the study and comply with all study procedures, 5. women of childbearing potential (wocbp) must be able and willing to use at least 1 highly effective method of contraception for a minimum of 3 months after the last dose of study vaccine. 6. wocbps must have a negative pregnancy test prior to each vaccination.