inclusion criteria: * age\> 18 years * laboratory-confirmed sars-cov-2 infection as determined by pcr or other validated commercial or public health assay * documented interstitial pneumonia requiring admission and at least two of the following: 1. fever ≥ 37.8ºc (tympanic) 2. il-6 in serum ≥ 25 ng / ml (in the absence of a previous dose of prednisone or equivalent\> 1 mg / kg) or pcr\> 5mg / dl 3. lymphocytes \<600 mm3 4. ferritin\> 300 mcg / l that doubles in 24 hours 5. ferritin\> 600 mcg / l in the first determination and ldh\> 250 u / l 6. d-dimer (\> 1 mg / l) * informed verbal or administration consent under urgent conditions, documented in the electronic medical record.

inclusion criteria: * age\> 18 years * laboratory-confirmed sars-cov-2 infection as determined by pcr or other validated commercial or public health assay * documented interstitial pneumonia requiring admission and at least two of the following: 1. fever ≥ 37.8ºc (tympanic) 2. il-6 in serum ≥ 25 ng / ml (in the absence of a previous dose of prednisone or equivalent\> 1 mg / kg) or pcr\> 5mg / dl 3. lymphocytes \<600 mm3 4. ferritin\> 300 mcg / l that doubles in 24 hours 5. ferritin\> 600 mcg / l in the first determination and ldh\> 250 u / l 6. d-dimer (\> 1 mg / l) * informed verbal or administration consent under urgent conditions, documented in the electronic medical record.

inclusion criteria: age> 18 years laboratory-confirmed sars-cov-2 infection as determined by pcr or other validated commercial or public health assay documented interstitial pneumonia requiring admission and at least two of the following: fever ≥ 37.8ºc (tympanic) il-6 in serum ≥ 25 ng / ml (in the absence of a previous dose of prednisone or equivalent> 1 mg / kg) or pcr> 5mg / dl lymphocytes <600 mm3 ferritin> 300 mcg / l that doubles in 24 hours ferritin> 600 mcg / l in the first determination and ldh> 250 u / l d-dimer (> 1 mg / l) informed verbal or administration consent under urgent conditions, documented in the electronic medical record.

inclusion criteria: age> 18 years laboratory-confirmed sars-cov-2 infection as determined by pcr or other validated commercial or public health assay documented interstitial pneumonia requiring admission and at least two of the following: fever ≥ 37.8ºc (tympanic) il-6 in serum ≥ 25 ng / ml (in the absence of a previous dose of prednisone or equivalent> 1 mg / kg) or pcr> 5mg / dl lymphocytes <600 mm3 ferritin> 300 mcg / l that doubles in 24 hours ferritin> 600 mcg / l in the first determination and ldh> 250 u / l d-dimer (> 1 mg / l) informed verbal or administration consent under urgent conditions, documented in the electronic medical record.

inclusion criteria: - age> 18 years - laboratory-confirmed sars-cov-2 infection as determined by pcr or other validated commercial or public health assay - documented interstitial pneumonia requiring admission and at least two of the following: 1. fever ≥ 37.8ºc (tympanic) 2. il-6 in serum ≥ 25 ng / ml (in the absence of a previous dose of prednisone or equivalent> 1 mg / kg) or pcr> 5mg / dl 3. lymphocytes <600 mm3 4. ferritin> 300 mcg / l that doubles in 24 hours 5. ferritin> 600 mcg / l in the first determination and ldh> 250 u / l 6. d-dimer (> 1 mg / l) - informed verbal or administration consent under urgent conditions, documented in the electronic medical record.

inclusion criteria: - age> 18 years - laboratory-confirmed sars-cov-2 infection as determined by pcr or other validated commercial or public health assay - documented interstitial pneumonia requiring admission and at least two of the following: 1. fever ≥ 37.8ºc (tympanic) 2. il-6 in serum ≥ 25 ng / ml (in the absence of a previous dose of prednisone or equivalent> 1 mg / kg) or pcr> 5mg / dl 3. lymphocytes <600 mm3 4. ferritin> 300 mcg / l that doubles in 24 hours 5. ferritin> 600 mcg / l in the first determination and ldh> 250 u / l 6. d-dimer (> 1 mg / l) - informed verbal or administration consent under urgent conditions, documented in the electronic medical record.