inclusion criteria: * male or female, age ≥ 18 years * laboratory (rt-pcr) confirmed infection with sars-cov2 * patient is either under invasive or non-invasive mechanical ventilation (including high flow nasal oxygen therapy). * diagnosis of ards according to the berlin definition of ards * onset of ards \<96 hours * patient with french social security system * a written informed consent by the designated substitute decision maker, if present. in the event of absence, the patient can be included by investigator's decision alone.

inclusion criteria: * male or female, age ≥ 18 years * laboratory (rt-pcr) confirmed infection with sars-cov2 * patient is either under invasive or non-invasive mechanical ventilation (including high flow nasal oxygen therapy). * diagnosis of ards according to the berlin definition of ards * onset of ards \<96 hours * patient with french social security system * a written informed consent by the designated substitute decision maker, if present. in the event of absence, the patient can be included by investigator's decision alone.

inclusion criteria: - male or female, age ≥ 18 years - laboratory (rt-pcr) confirmed infection with sars-cov2 - patient is either under invasive or non-invasive mechanical ventilation (including high flow nasal oxygen therapy). - diagnosis of ards according to the berlin definition of ards - onset of ards <96 hours - patient with french social security system - a written informed consent by the designated substitute decision maker, if present. in the event of absence, the patient can be included by investigator's decision alone.

inclusion criteria: - male or female, age ≥ 18 years - laboratory (rt-pcr) confirmed infection with sars-cov2 - patient is either under invasive or non-invasive mechanical ventilation (including high flow nasal oxygen therapy). - diagnosis of ards according to the berlin definition of ards - onset of ards <96 hours - patient with french social security system - a written informed consent by the designated substitute decision maker, if present. in the event of absence, the patient can be included by investigator's decision alone.

inclusion criteria: - male or female, age ≥ 18 years - laboratory (rt-pcr) confirmed infection with sars-cov2 - patient is intubated and mechanically ventilated - diagnosis of ards according to the berlin definition of ards - onset of ards <96 hours - patient with french social security system - a written informed consent by the designated substitute decision maker, if present. in the event of absence, the patient can be included by investigator's decision alone.

inclusion criteria: - male or female, age ≥ 18 years - laboratory (rt-pcr) confirmed infection with sars-cov2 - patient is intubated and mechanically ventilated - diagnosis of ards according to the berlin definition of ards - onset of ards <96 hours - patient with french social security system - a written informed consent by the designated substitute decision maker, if present. in the event of absence, the patient can be included by investigator's decision alone.