* immunosuppression * pregnancy \& lactation * chronic underlying medical illness * known allergy to (components of) the bcg vaccine or serious adverse events to prior bcg administration * known active or latent mycobacterium tuberculosis or with another mycobacterial species. * fever (\>38 c) within the past 24 hours * current bacterial infection * recent viral infection * refusal of doing tuberculin test in the first group

* immunosuppression * pregnancy \& lactation * chronic underlying medical illness * known allergy to (components of) the bcg vaccine or serious adverse events to prior bcg administration * known active or latent mycobacterium tuberculosis or with another mycobacterial species. * fever (\>38 c) within the past 24 hours * current bacterial infection * recent viral infection * refusal of doing tuberculin test in the first group

- immunosuppression - pregnancy & lactation - chronic underlying medical illness - known allergy to (components of) the bcg vaccine or serious adverse events to prior bcg administration - known active or latent mycobacterium tuberculosis or with another mycobacterial species. - fever (>38 c) within the past 24 hours - current bacterial infection - recent viral infection - refusal of doing tuberculin test in the first group

- immunosuppression - pregnancy & lactation - chronic underlying medical illness - known allergy to (components of) the bcg vaccine or serious adverse events to prior bcg administration - known active or latent mycobacterium tuberculosis or with another mycobacterial species. - fever (>38 c) within the past 24 hours - current bacterial infection - recent viral infection - refusal of doing tuberculin test in the first group