inclusion criteria: * body mass index (bmi) ≥ 18.0 and ≤ 32.0 kg/m2 at screening and weighs at least 50 kg. * medically healthy with no clinically significant medical history, physical examination, spirometry, vital signs or ecgs. * forced expiratory volume in 1 second (fev1) ≥80%. * no clinically significant abnormalities in the results of laboratory evaluations. * female subjects must be either of non-childbearing potential or if of childbearing potential, subject must not be pregnant or breastfeeding, and must agree to use a highly effective birth control method. * male subjects must agree to use condoms, in addition to the use of highly effective pregnancy prevention measures with female partners of childbearing potential. * understands the correct technique for the use the nebulizer device(s). * other inclusion criteria apply

inclusion criteria: * body mass index (bmi) ≥ 18.0 and ≤ 32.0 kg/m2 at screening and weighs at least 50 kg. * medically healthy with no clinically significant medical history, physical examination, spirometry, vital signs or ecgs. * forced expiratory volume in 1 second (fev1) ≥80%. * no clinically significant abnormalities in the results of laboratory evaluations. * female subjects must be either of non-childbearing potential or if of childbearing potential, subject must not be pregnant or breastfeeding, and must agree to use a highly effective birth control method. * male subjects must agree to use condoms, in addition to the use of highly effective pregnancy prevention measures with female partners of childbearing potential. * understands the correct technique for the use the nebulizer device(s). * other inclusion criteria apply

inclusion criteria: - body mass index (bmi) ≥ 18.0 and ≤ 32.0 kg/m2 at screening and weighs at least 50 kg. - medically healthy with no clinically significant medical history, physical examination, spirometry, vital signs or ecgs. - forced expiratory volume in 1 second (fev1) ≥80%. - no clinically significant abnormalities in the results of laboratory evaluations. - female subjects must be either of non-childbearing potential or if of childbearing potential, subject must not be pregnant or breastfeeding, and must agree to use a highly effective birth control method. - male subjects must agree to use condoms, in addition to the use of highly effective pregnancy prevention measures with female partners of childbearing potential. - understands the correct technique for the use the nebulizer device(s). - other inclusion criteria apply

inclusion criteria: - body mass index (bmi) ≥ 18.0 and ≤ 32.0 kg/m2 at screening and weighs at least 50 kg. - medically healthy with no clinically significant medical history, physical examination, spirometry, vital signs or ecgs. - forced expiratory volume in 1 second (fev1) ≥80%. - no clinically significant abnormalities in the results of laboratory evaluations. - female subjects must be either of non-childbearing potential or if of childbearing potential, subject must not be pregnant or breastfeeding, and must agree to use a highly effective birth control method. - male subjects must agree to use condoms, in addition to the use of highly effective pregnancy prevention measures with female partners of childbearing potential. - understands the correct technique for the use the nebulizer device(s). - other inclusion criteria apply