* history or presence of clinically significant medical or psychiatric condition. * abnormal ecg measurements at screening. * any signs of respiratory tract infection within 6 weeks of screening. * subject who has a current bacterial, parasitic, fungal, or viral infection; any infection requiring hospitalization or intravenous antibiotics within 6 months prior to screening. * positive test for sars-cov-2 * subject has any condition of the oro-laryngeal or respiratory tract. * uses or has used tobacco or nicotine-containing products (e.g., cigarettes, cigars, chewing tobacco, snuff, patches etc.) within 6 months prior to screening * additional exclusion criteria apply

* history or presence of clinically significant medical or psychiatric condition. * abnormal ecg measurements at screening. * any signs of respiratory tract infection within 6 weeks of screening. * subject who has a current bacterial, parasitic, fungal, or viral infection; any infection requiring hospitalization or intravenous antibiotics within 6 months prior to screening. * positive test for sars-cov-2 * subject has any condition of the oro-laryngeal or respiratory tract. * uses or has used tobacco or nicotine-containing products (e.g., cigarettes, cigars, chewing tobacco, snuff, patches etc.) within 6 months prior to screening * additional exclusion criteria apply

- history or presence of clinically significant medical or psychiatric condition. - abnormal ecg measurements at screening. - any signs of respiratory tract infection within 6 weeks of screening. - subject who has a current bacterial, parasitic, fungal, or viral infection; any infection requiring hospitalization or intravenous antibiotics within 6 months prior to screening. - positive test for sars-cov-2 - subject has any condition of the oro-laryngeal or respiratory tract. - uses or has used tobacco or nicotine-containing products (e.g., cigarettes, cigars, chewing tobacco, snuff, patches etc.) within 6 months prior to screening - additional exclusion criteria apply

- history or presence of clinically significant medical or psychiatric condition. - abnormal ecg measurements at screening. - any signs of respiratory tract infection within 6 weeks of screening. - subject who has a current bacterial, parasitic, fungal, or viral infection; any infection requiring hospitalization or intravenous antibiotics within 6 months prior to screening. - positive test for sars-cov-2 - subject has any condition of the oro-laryngeal or respiratory tract. - uses or has used tobacco or nicotine-containing products (e.g., cigarettes, cigars, chewing tobacco, snuff, patches etc.) within 6 months prior to screening - additional exclusion criteria apply