inclusion criteria: * adults aged 18 years or older * ards according to the berlin definition * covid-19 pneumonia confirmed by rt-pcr * acute respiratory failure not fully explained by left ventricular failure or sodium overload * bilateral pulmonary radiological opacities not fully explained by pleural effusions or atelectasis or nodules * invasive mechanical ventilation with pao2/fio2 ≤ 150 mm hg and peep ≥ 5 cm h2o with a tidal volume below or equal to 6 ml per kilogram of predicted body weight * continuous intravenous sedation as part of ards treatment

inclusion criteria: * adults aged 18 years or older * ards according to the berlin definition * covid-19 pneumonia confirmed by rt-pcr * acute respiratory failure not fully explained by left ventricular failure or sodium overload * bilateral pulmonary radiological opacities not fully explained by pleural effusions or atelectasis or nodules * invasive mechanical ventilation with pao2/fio2 ≤ 150 mm hg and peep ≥ 5 cm h2o with a tidal volume below or equal to 6 ml per kilogram of predicted body weight * continuous intravenous sedation as part of ards treatment

inclusion criteria: - adults aged 18 years or older - ards according to the berlin definition - covid-19 pneumonia confirmed by rt-pcr - acute respiratory failure not fully explained by left ventricular failure or sodium overload - bilateral pulmonary radiological opacities not fully explained by pleural effusions or atelectasis or nodules - invasive mechanical ventilation with pao2/fio2 ≤ 150 mm hg and peep ≥ 5 cm h2o with a tidal volume below or equal to 6 ml per kilogram of predicted body weight - continuous intravenous sedation as part of ards treatment

inclusion criteria: - adults aged 18 years or older - ards according to the berlin definition - covid-19 pneumonia confirmed by rt-pcr - acute respiratory failure not fully explained by left ventricular failure or sodium overload - bilateral pulmonary radiological opacities not fully explained by pleural effusions or atelectasis or nodules - invasive mechanical ventilation with pao2/fio2 ≤ 150 mm hg and peep ≥ 5 cm h2o with a tidal volume below or equal to 6 ml per kilogram of predicted body weight - continuous intravenous sedation as part of ards treatment