inclusion criteria: 1. subjects must provide informed consent in accordance with requirements of the study center's institutional review board (irb) or eithics committee prior to the initiation of any protocol-required procedures 2. subjects must agree to provide all requested demographic information (i.e. gender, race) 3. subjects must be able to read and understand english or spanish 4. subjects must be over the age of 18 years 5. subjects must have laboratory-confirmed sars-cov-2 infection as determined by pcr-based commercial or public health assay 6. subjects must have symptoms that require hospitalization with supplemental oxygen and / or non-invasive ventilation as determined by the admitting physician. the maximum nasal cannula o2 concentration should be determined by the treating clinician and the limitations of the specific equipment 7. subjects must be willing and able to comply with study-related procedures/assessments

inclusion criteria: 1. subjects must provide informed consent in accordance with requirements of the study center's institutional review board (irb) or eithics committee prior to the initiation of any protocol-required procedures 2. subjects must agree to provide all requested demographic information (i.e. gender, race) 3. subjects must be able to read and understand english or spanish 4. subjects must be over the age of 18 years 5. subjects must have laboratory-confirmed sars-cov-2 infection as determined by pcr-based commercial or public health assay 6. subjects must have symptoms that require hospitalization with supplemental oxygen and / or non-invasive ventilation as determined by the admitting physician. the maximum nasal cannula o2 concentration should be determined by the treating clinician and the limitations of the specific equipment 7. subjects must be willing and able to comply with study-related procedures/assessments

inclusion criteria: subjects must provide informed consent in accordance with requirements of the study center's institutional review board (irb) or eithics committee prior to the initiation of any protocol-required procedures subjects must agree to provide all requested demographic information (i.e. gender, race) subjects must be able to read and understand english or spanish subjects must be over the age of 18 years subjects must have laboratory-confirmed sars-cov-2 infection as determined by pcr-based commercial or public health assay subjects must have symptoms that require hospitalization with supplemental oxygen and / or non-invasive ventilation as determined by the admitting physician. the maximum nasal cannula o2 concentration should be determined by the treating clinician and the limitations of the specific equipment subjects must be willing and able to comply with study-related procedures/assessments

inclusion criteria: subjects must provide informed consent in accordance with requirements of the study center's institutional review board (irb) or eithics committee prior to the initiation of any protocol-required procedures subjects must agree to provide all requested demographic information (i.e. gender, race) subjects must be able to read and understand english or spanish subjects must be over the age of 18 years subjects must have laboratory-confirmed sars-cov-2 infection as determined by pcr-based commercial or public health assay subjects must have symptoms that require hospitalization with supplemental oxygen and / or non-invasive ventilation as determined by the admitting physician. the maximum nasal cannula o2 concentration should be determined by the treating clinician and the limitations of the specific equipment subjects must be willing and able to comply with study-related procedures/assessments

inclusion criteria: 1. subjects must provide informed consent in accordance with requirements of the study center's institutional review board (irb) or eithics committee prior to the initiation of any protocol-required procedures 2. subjects must agree to provide all requested demographic information (i.e. gender, race) 3. subjects must be able to read and understand english or spanish 4. subjects must be over the age of 18 years 5. subjects must have laboratory-confirmed sars-cov-2 infection as determined by pcr-based commercial or public health assay 6. subjects must have symptoms that require hospitalization with supplemental oxygen and / or non-invasive ventilation as determined by the admitting physician. the maximum nasal cannula o2 concentration should be determined by the treating clinician and the limitations of the specific equipment 7. subjects must be willing and able to comply with study-related procedures/assessments

inclusion criteria: 1. subjects must provide informed consent in accordance with requirements of the study center's institutional review board (irb) or eithics committee prior to the initiation of any protocol-required procedures 2. subjects must agree to provide all requested demographic information (i.e. gender, race) 3. subjects must be able to read and understand english or spanish 4. subjects must be over the age of 18 years 5. subjects must have laboratory-confirmed sars-cov-2 infection as determined by pcr-based commercial or public health assay 6. subjects must have symptoms that require hospitalization with supplemental oxygen and / or non-invasive ventilation as determined by the admitting physician. the maximum nasal cannula o2 concentration should be determined by the treating clinician and the limitations of the specific equipment 7. subjects must be willing and able to comply with study-related procedures/assessments