inclusion criteria: * age greater than 18 years * positive sars-cov-2 testing or consistent clinical syndrome (based on clinical picture e.g. characteristic infiltrates on chest x-ray, laboratory findings, and with agreement by two physicians) in patients under investigation (puis). * onset of symptoms \< 7 days from date of enrollment * oxygen saturation of \>94% on room air with defined risk factors (table 1) consistent with moderate disease or oxygen saturation of \< 94% on room air consistent with severe disease * ability and willingness to comply with study procedures

inclusion criteria: * age greater than 18 years * positive sars-cov-2 testing or consistent clinical syndrome (based on clinical picture e.g. characteristic infiltrates on chest x-ray, laboratory findings, and with agreement by two physicians) in patients under investigation (puis). * onset of symptoms \< 7 days from date of enrollment * oxygen saturation of \>94% on room air with defined risk factors (table 1) consistent with moderate disease or oxygen saturation of \< 94% on room air consistent with severe disease * ability and willingness to comply with study procedures

inclusion criteria: - age greater than 18 years - positive sars-cov-2 testing or consistent clinical syndrome (based on clinical picture e.g. characteristic infiltrates on chest x-ray, laboratory findings, and with agreement by two physicians) in patients under investigation (puis). - onset of symptoms < 7 days from date of enrollment - oxygen saturation of >94% on room air with defined risk factors (table 1) consistent with moderate disease or oxygen saturation of < 94% on room air consistent with severe disease - ability and willingness to comply with study procedures

inclusion criteria: - age greater than 18 years - positive sars-cov-2 testing or consistent clinical syndrome (based on clinical picture e.g. characteristic infiltrates on chest x-ray, laboratory findings, and with agreement by two physicians) in patients under investigation (puis). - onset of symptoms < 7 days from date of enrollment - oxygen saturation of >94% on room air with defined risk factors (table 1) consistent with moderate disease or oxygen saturation of < 94% on room air consistent with severe disease - ability and willingness to comply with study procedures