inclusion criteria: * • clinical score greater than 6 * patients with clinical symptoms less than 5 days old. * men and women at least 40 years old, able and willing to give informed consent; * any patient over the age of 18 with a ct scan in favor of covid-19; * ambulatory or hospitalized environment; * patient with dyspnea or with a positive gait test; * the patient must have at least one of the following high risk criteria: 70 years or older, obesity (bmi ≥ 30 kg / m2), diabetes mellitus, uncontrolled hypertension (systolic blood pressure ≥ 150 mm hg), respiratory disease known (including asthma or chronic obstructive pulmonary disease), known heart failure, known coronary artery disease, fever ≥ 38.4 ° c within the last 48 hours, dyspnea at the time of presentation, bicytopenia, pancytopenia or a combination of a number high neutrophils and low lymphocytes count; * the patient is not of childbearing age, defined as postmenopausal for at least 1 year or surgically sterile, or is of childbearing age and uses at least one method of contraception and preferably two complementary forms of contraception comprising a method of barrier throughout the study and for 30 days after the end of the study; * the patient must be able and willing to comply with the requirements of this study protocol.

inclusion criteria: * • clinical score greater than 6 * patients with clinical symptoms less than 5 days old. * men and women at least 40 years old, able and willing to give informed consent; * any patient over the age of 18 with a ct scan in favor of covid-19; * ambulatory or hospitalized environment; * patient with dyspnea or with a positive gait test; * the patient must have at least one of the following high risk criteria: 70 years or older, obesity (bmi ≥ 30 kg / m2), diabetes mellitus, uncontrolled hypertension (systolic blood pressure ≥ 150 mm hg), respiratory disease known (including asthma or chronic obstructive pulmonary disease), known heart failure, known coronary artery disease, fever ≥ 38.4 ° c within the last 48 hours, dyspnea at the time of presentation, bicytopenia, pancytopenia or a combination of a number high neutrophils and low lymphocytes count; * the patient is not of childbearing age, defined as postmenopausal for at least 1 year or surgically sterile, or is of childbearing age and uses at least one method of contraception and preferably two complementary forms of contraception comprising a method of barrier throughout the study and for 30 days after the end of the study; * the patient must be able and willing to comply with the requirements of this study protocol.

inclusion criteria: - • clinical score greater than 6 - patients with clinical symptoms less than 5 days old. - men and women at least 40 years old, able and willing to give informed consent; - any patient over the age of 18 with a ct scan in favor of covid-19; - ambulatory or hospitalized environment; - patient with dyspnea or with a positive gait test; - the patient must have at least one of the following high risk criteria: 70 years or older, obesity (bmi ≥ 30 kg / m2), diabetes mellitus, uncontrolled hypertension (systolic blood pressure ≥ 150 mm hg), respiratory disease known (including asthma or chronic obstructive pulmonary disease), known heart failure, known coronary artery disease, fever ≥ 38.4 ° c within the last 48 hours, dyspnea at the time of presentation, bicytopenia, pancytopenia or a combination of a number high neutrophils and low lymphocytes count; - the patient is not of childbearing age, defined as postmenopausal for at least 1 year or surgically sterile, or is of childbearing age and uses at least one method of contraception and preferably two complementary forms of contraception comprising a method of barrier throughout the study and for 30 days after the end of the study; - the patient must be able and willing to comply with the requirements of this study protocol.

inclusion criteria: - • clinical score greater than 6 - patients with clinical symptoms less than 5 days old. - men and women at least 40 years old, able and willing to give informed consent; - any patient over the age of 18 with a ct scan in favor of covid-19; - ambulatory or hospitalized environment; - patient with dyspnea or with a positive gait test; - the patient must have at least one of the following high risk criteria: 70 years or older, obesity (bmi ≥ 30 kg / m2), diabetes mellitus, uncontrolled hypertension (systolic blood pressure ≥ 150 mm hg), respiratory disease known (including asthma or chronic obstructive pulmonary disease), known heart failure, known coronary artery disease, fever ≥ 38.4 ° c within the last 48 hours, dyspnea at the time of presentation, bicytopenia, pancytopenia or a combination of a number high neutrophils and low lymphocytes count; - the patient is not of childbearing age, defined as postmenopausal for at least 1 year or surgically sterile, or is of childbearing age and uses at least one method of contraception and preferably two complementary forms of contraception comprising a method of barrier throughout the study and for 30 days after the end of the study; - the patient must be able and willing to comply with the requirements of this study protocol.