inclusion criteria: * age ≥ 18 years ; * severe covid-19 pneumonia, defined by: * a newly-appeared pulmonary parenchymal infiltrate; and * a positive rt-pcr (either upper or lower respiratory tract) for covid-19 (sars-cov-2); and * who progression scale ≥ 5 (on the who ordinal scale) * written informed consent (patient, next of skin or emergency situation). * in view of the exceptional and urgent situation, affiliation to a social security scheme will not be a criterion for inclusion.

inclusion criteria: * age ≥ 18 years ; * severe covid-19 pneumonia, defined by: * a newly-appeared pulmonary parenchymal infiltrate; and * a positive rt-pcr (either upper or lower respiratory tract) for covid-19 (sars-cov-2); and * who progression scale ≥ 5 (on the who ordinal scale) * written informed consent (patient, next of skin or emergency situation). * in view of the exceptional and urgent situation, affiliation to a social security scheme will not be a criterion for inclusion.

inclusion criteria: age ≥ 18 years ; severe covid-19 pneumonia, defined by: a newly-appeared pulmonary parenchymal infiltrate; and a positive rt-pcr (either upper or lower respiratory tract) for covid-19 (sars-cov-2); and who progression scale ≥ 5 (on the who ordinal scale) written informed consent (patient, next of skin or emergency situation). in view of the exceptional and urgent situation, affiliation to a social security scheme will not be a criterion for inclusion.

inclusion criteria: age ≥ 18 years ; severe covid-19 pneumonia, defined by: a newly-appeared pulmonary parenchymal infiltrate; and a positive rt-pcr (either upper or lower respiratory tract) for covid-19 (sars-cov-2); and who progression scale ≥ 5 (on the who ordinal scale) written informed consent (patient, next of skin or emergency situation). in view of the exceptional and urgent situation, affiliation to a social security scheme will not be a criterion for inclusion.

inclusion criteria: - age ≥ 18 years ; - severe covid-19 pneumonia, defined by: - a newly-appeared pulmonary parenchymal infiltrate; and - a positive rt-pcr (either upper or lower respiratory tract) for covid-19 (sars-cov-2); and - who progression scale ≥ 5 - written informed consent (patient, next of skin or emergency situation). - in view of the exceptional and urgent situation, affiliation to a social security scheme will not be a criterion for inclusion.

inclusion criteria: - age ≥ 18 years ; - severe covid-19 pneumonia, defined by: - a newly-appeared pulmonary parenchymal infiltrate; and - a positive rt-pcr (either upper or lower respiratory tract) for covid-19 (sars-cov-2); and - who progression scale ≥ 5 - written informed consent (patient, next of skin or emergency situation). - in view of the exceptional and urgent situation, affiliation to a social security scheme will not be a criterion for inclusion.