common criteria: * need for assisted ventilation that makes oral consumption of the product under study impossible * history of allergy, idiosyncrasy, hypersensitivity or adverse reactions to the active principle or to any of the excipients. * history or evidence of any medical conditions or medication use that, in the opinion of the principal investigator, could affect the safety of the subjects or interfere with the study evaluations * subjects in situation of last days covid-19 vaccine groups: * subjects in whom the covid-19 vaccine is contraindicated. * a history of frailty or comorbidity that indicates a situation of clinical instability. * history or evidence of any medical conditions or drug use that, in the opinion of the principal investigator, could affect the safety of subjects or interfere with study evaluations.

common criteria: * need for assisted ventilation that makes oral consumption of the product under study impossible * history of allergy, idiosyncrasy, hypersensitivity or adverse reactions to the active principle or to any of the excipients. * history or evidence of any medical conditions or medication use that, in the opinion of the principal investigator, could affect the safety of the subjects or interfere with the study evaluations * subjects in situation of last days covid-19 vaccine groups: * subjects in whom the covid-19 vaccine is contraindicated. * a history of frailty or comorbidity that indicates a situation of clinical instability. * history or evidence of any medical conditions or drug use that, in the opinion of the principal investigator, could affect the safety of subjects or interfere with study evaluations.

common criteria: - need for assisted ventilation that makes oral consumption of the product under study impossible - history of allergy, idiosyncrasy, hypersensitivity or adverse reactions to the active principle or to any of the excipients. - history or evidence of any medical conditions or medication use that, in the opinion of the principal investigator, could affect the safety of the subjects or interfere with the study evaluations - subjects in situation of last days covid-19 vaccine groups: - subjects in whom the covid-19 vaccine is contraindicated. - a history of frailty or comorbidity that indicates a situation of clinical instability. - history or evidence of any medical conditions or drug use that, in the opinion of the principal investigator, could affect the safety of subjects or interfere with study evaluations.

common criteria: - need for assisted ventilation that makes oral consumption of the product under study impossible - history of allergy, idiosyncrasy, hypersensitivity or adverse reactions to the active principle or to any of the excipients. - history or evidence of any medical conditions or medication use that, in the opinion of the principal investigator, could affect the safety of the subjects or interfere with the study evaluations - subjects in situation of last days covid-19 vaccine groups: - subjects in whom the covid-19 vaccine is contraindicated. - a history of frailty or comorbidity that indicates a situation of clinical instability. - history or evidence of any medical conditions or drug use that, in the opinion of the principal investigator, could affect the safety of subjects or interfere with study evaluations.