inclusion criteria: 1. patients included in the corimuno-19 cohort 2. patients with c-reactive protein level (crp) \> 25 mg / l the day or the day before the infusion) 3. patients belonging to one of the 2 following groups: * group 1: patients meeting all of the following criteria: 1) requiring more than 3l/min of oxygen; 2) who progression scale = 5; 3) no niv or high flow * group 2: patients with respiratory failure and (requiring mechanical ventilation or niv or high flow), with a who progression scale ≥ 6, and no do-not-resuscitate (dnr) order

inclusion criteria: 1. patients included in the corimuno-19 cohort 2. patients with c-reactive protein level (crp) \> 25 mg / l the day or the day before the infusion) 3. patients belonging to one of the 2 following groups: * group 1: patients meeting all of the following criteria: 1) requiring more than 3l/min of oxygen; 2) who progression scale = 5; 3) no niv or high flow * group 2: patients with respiratory failure and (requiring mechanical ventilation or niv or high flow), with a who progression scale ≥ 6, and no do-not-resuscitate (dnr) order

inclusion criteria: patients included in the corimuno-19 cohort patients with c-reactive protein level (crp) > 25 mg / l the day or the day before the infusion) patients belonging to one of the 2 following groups: group 1: patients meeting all of the following criteria: 1) requiring more than 3l/min of oxygen; 2) who progression scale = 5; 3) no niv or high flow group 2: patients with respiratory failure and (requiring mechanical ventilation or niv or high flow), with a who progression scale ≥ 6, and no do-not-resuscitate (dnr) order

inclusion criteria: patients included in the corimuno-19 cohort patients with c-reactive protein level (crp) > 25 mg / l the day or the day before the infusion) patients belonging to one of the 2 following groups: group 1: patients meeting all of the following criteria: 1) requiring more than 3l/min of oxygen; 2) who progression scale = 5; 3) no niv or high flow group 2: patients with respiratory failure and (requiring mechanical ventilation or niv or high flow), with a who progression scale ≥ 6, and no do-not-resuscitate (dnr) order

inclusion criteria: 1. patients included in the corimuno-19 cohort 2. patients with c-reactive protein level (crp) > 25 mg / l the day or the day before the infusion) 3. patients belonging to one of the 2 following groups: - group 1: patients meeting all of the following criteria: 1) requiring more than 3l/min of oxygen; 2) who progression scale = 5; 3) no niv or high flow - group 2: patients with respiratory failure and (requiring mechanical ventilation or niv or high flow), with a who progression scale ≥ 6, and no do-not-resuscitate (dnr) order

inclusion criteria: 1. patients included in the corimuno-19 cohort 2. patients with c-reactive protein level (crp) > 25 mg / l the day or the day before the infusion) 3. patients belonging to one of the 2 following groups: - group 1: patients meeting all of the following criteria: 1) requiring more than 3l/min of oxygen; 2) who progression scale = 5; 3) no niv or high flow - group 2: patients with respiratory failure and (requiring mechanical ventilation or niv or high flow), with a who progression scale ≥ 6, and no do-not-resuscitate (dnr) order