* patients with exclusion criteria to the corimuno-19 cohort. * known hypersensitivity to anakinra or to any of their excipients. * pregnancy * current documented bacterial infection. * patient with any of following laboratory results out of the ranges detailed below at screening: * absolute neutrophil count (anc) ≤ 1.0 x 109/l * haemoglobin level: no limitation * platelets (plt) \< 50 g /l * sgot or sgpt \> 5n * severe renal insufficiency with glomerular filtration rate \< 30 ml / mn

* patients with exclusion criteria to the corimuno-19 cohort. * known hypersensitivity to anakinra or to any of their excipients. * pregnancy * current documented bacterial infection. * patient with any of following laboratory results out of the ranges detailed below at screening: * absolute neutrophil count (anc) ≤ 1.0 x 109/l * haemoglobin level: no limitation * platelets (plt) \< 50 g /l * sgot or sgpt \> 5n * severe renal insufficiency with glomerular filtration rate \< 30 ml / mn

- patients with exclusion criteria to the corimuno-19 cohort. - known hypersensitivity to anakinra or to any of their excipients. - pregnancy - current documented bacterial infection. - patient with any of following laboratory results out of the ranges detailed below at screening: - absolute neutrophil count (anc) ≤ 1.0 x 109/l - haemoglobin level: no limitation - platelets (plt) < 50 g /l - sgot or sgpt > 5n - severe renal insufficiency with glomerular filtration rate < 30 ml / mn

- patients with exclusion criteria to the corimuno-19 cohort. - known hypersensitivity to anakinra or to any of their excipients. - pregnancy - current documented bacterial infection. - patient with any of following laboratory results out of the ranges detailed below at screening: - absolute neutrophil count (anc) ≤ 1.0 x 109/l - haemoglobin level: no limitation - platelets (plt) < 50 g /l - sgot or sgpt > 5n - severe renal insufficiency with glomerular filtration rate < 30 ml / mn