* history of anaphylaxis, urticarial, or other significant adverse reaction requiring medical intervention after receipt of a vaccine. * female who is pregnant or positive in pregnancy test at screening or just prior to each vaccination administration. * female who is breast-feeding or plans to breastfeed from the time of the first vaccination through 60 days after the last vaccination. * any acute illness, as determined by the study investigator 3 days before first vaccination (these subjects can be re-scheduled). * any major surgery one month before first vaccination (these subjects can be -rescheduled). * known hiv antibody positive. * known active hepatitis b and hepatitis c disease. * previous exposure to sars-cov-2 or receipt of an investigational or licensed product for the prevention of covid-19, mers or sars. * have history of guillain-barre syndrome. * subjects who take part in another clinical study within 12 weeks prior to the day of informed consent. * immune deficiency/disorder, whether due to genetic defect, immunodeficiency disease or immunosuppressive therapy. * subjects who plan to or are undergoing anti-cancer therapy. * platelet disorder or other bleeding disorder may cause injection contraindication. * prior chronic administration of immunosuppressant or corticosteroids, cytotoxic treatment in last 6 months before first vaccination. * prior administration of immunoglobulins and/or any blood products in last 4 months before first vaccination. * receipt of any seasonal or pandemic influenza vaccine within 14 days, or any other non-study vaccine within 28 days, before study intervention administration. * anticipated receipt of any seasonal or pandemic influenza vaccine within 14 days, or any other nonstudy vaccine within 28 days, after study intervention administration. * receipt of short-term (\<14 days) systemic corticosteroids. study intervention administration should be delayed until systemic corticosteroid use has been discontinued for at least 28 days. inhaled/nebulized, intra-articular, intrabursal, or topical (skin or eyes) corticosteroids are permitted. * loss or donation of blood over 500 ml within 3 months prior to screening visit or intention to donate blood or blood products for transfusion during the study. * any medical disease or condition that, in the opinion of the study investigator, may confound the results of the study or pose an additional risk to the subjects by their participation in the study. * employees at the investigator's site, of the sponsor or the contract research organization (cro) who directly involved in the conduct of the study.

* history of anaphylaxis, urticarial, or other significant adverse reaction requiring medical intervention after receipt of a vaccine. * female who is pregnant or positive in pregnancy test at screening or just prior to each vaccination administration. * female who is breast-feeding or plans to breastfeed from the time of the first vaccination through 60 days after the last vaccination. * any acute illness, as determined by the study investigator 3 days before first vaccination (these subjects can be re-scheduled). * any major surgery one month before first vaccination (these subjects can be -rescheduled). * known hiv antibody positive. * known active hepatitis b and hepatitis c disease. * previous exposure to sars-cov-2 or receipt of an investigational or licensed product for the prevention of covid-19, mers or sars. * have history of guillain-barre syndrome. * subjects who take part in another clinical study within 12 weeks prior to the day of informed consent. * immune deficiency/disorder, whether due to genetic defect, immunodeficiency disease or immunosuppressive therapy. * subjects who plan to or are undergoing anti-cancer therapy. * platelet disorder or other bleeding disorder may cause injection contraindication. * prior chronic administration of immunosuppressant or corticosteroids, cytotoxic treatment in last 6 months before first vaccination. * prior administration of immunoglobulins and/or any blood products in last 4 months before first vaccination. * receipt of any seasonal or pandemic influenza vaccine within 14 days, or any other non-study vaccine within 28 days, before study intervention administration. * anticipated receipt of any seasonal or pandemic influenza vaccine within 14 days, or any other nonstudy vaccine within 28 days, after study intervention administration. * receipt of short-term (\<14 days) systemic corticosteroids. study intervention administration should be delayed until systemic corticosteroid use has been discontinued for at least 28 days. inhaled/nebulized, intra-articular, intrabursal, or topical (skin or eyes) corticosteroids are permitted. * loss or donation of blood over 500 ml within 3 months prior to screening visit or intention to donate blood or blood products for transfusion during the study. * any medical disease or condition that, in the opinion of the study investigator, may confound the results of the study or pose an additional risk to the subjects by their participation in the study. * employees at the investigator's site, of the sponsor or the contract research organization (cro) who directly involved in the conduct of the study.

- history of anaphylaxis, urticarial, or other significant adverse reaction requiring medical intervention after receipt of a vaccine. - female who is pregnant or positive in pregnancy test at screening or just prior to each vaccination administration. - female who is breast-feeding or plans to breastfeed from the time of the first vaccination through 60 days after the last vaccination. - any acute illness, as determined by the study investigator 3 days before first vaccination (these subjects can be re-scheduled). - any major surgery one month before first vaccination (these subjects can be -rescheduled). - known hiv antibody positive. - known active hepatitis b and hepatitis c disease. - previous exposure to sars-cov-2 or receipt of an investigational or licensed product for the prevention of covid-19, mers or sars. - have history of guillain-barre syndrome. - subjects who take part in another clinical study within 12 weeks prior to the day of informed consent. - immune deficiency/disorder, whether due to genetic defect, immunodeficiency disease or immunosuppressive therapy. - subjects who plan to or are undergoing anti-cancer therapy. - platelet disorder or other bleeding disorder may cause injection contraindication. - prior chronic administration of immunosuppressant or corticosteroids, cytotoxic treatment in last 6 months before first vaccination. - prior administration of immunoglobulins and/or any blood products in last 4 months before first vaccination. - receipt of any seasonal or pandemic influenza vaccine within 14 days, or any other non-study vaccine within 28 days, before study intervention administration. - anticipated receipt of any seasonal or pandemic influenza vaccine within 14 days, or any other nonstudy vaccine within 28 days, after study intervention administration. - receipt of short-term (<14 days) systemic corticosteroids. study intervention administration should be delayed until systemic corticosteroid use has been discontinued for at least 28 days. inhaled/nebulized, intra-articular, intrabursal, or topical (skin or eyes) corticosteroids are permitted. - loss or donation of blood over 500 ml within 3 months prior to screening visit or intention to donate blood or blood products for transfusion during the study. - any medical disease or condition that, in the opinion of the study investigator, may confound the results of the study or pose an additional risk to the subjects by their participation in the study. - employees at the investigator's site, of the sponsor or the contract research organization (cro) who directly involved in the conduct of the study.

- history of anaphylaxis, urticarial, or other significant adverse reaction requiring medical intervention after receipt of a vaccine. - female who is pregnant or positive in pregnancy test at screening or just prior to each vaccination administration. - female who is breast-feeding or plans to breastfeed from the time of the first vaccination through 60 days after the last vaccination. - any acute illness, as determined by the study investigator 3 days before first vaccination (these subjects can be re-scheduled). - any major surgery one month before first vaccination (these subjects can be -rescheduled). - known hiv antibody positive. - known active hepatitis b and hepatitis c disease. - previous exposure to sars-cov-2 or receipt of an investigational or licensed product for the prevention of covid-19, mers or sars. - have history of guillain-barre syndrome. - subjects who take part in another clinical study within 12 weeks prior to the day of informed consent. - immune deficiency/disorder, whether due to genetic defect, immunodeficiency disease or immunosuppressive therapy. - subjects who plan to or are undergoing anti-cancer therapy. - platelet disorder or other bleeding disorder may cause injection contraindication. - prior chronic administration of immunosuppressant or corticosteroids, cytotoxic treatment in last 6 months before first vaccination. - prior administration of immunoglobulins and/or any blood products in last 4 months before first vaccination. - receipt of any seasonal or pandemic influenza vaccine within 14 days, or any other non-study vaccine within 28 days, before study intervention administration. - anticipated receipt of any seasonal or pandemic influenza vaccine within 14 days, or any other nonstudy vaccine within 28 days, after study intervention administration. - receipt of short-term (<14 days) systemic corticosteroids. study intervention administration should be delayed until systemic corticosteroid use has been discontinued for at least 28 days. inhaled/nebulized, intra-articular, intrabursal, or topical (skin or eyes) corticosteroids are permitted. - loss or donation of blood over 500 ml within 3 months prior to screening visit or intention to donate blood or blood products for transfusion during the study. - any medical disease or condition that, in the opinion of the study investigator, may confound the results of the study or pose an additional risk to the subjects by their participation in the study. - employees at the investigator's site, of the sponsor or the contract research organization (cro) who directly involved in the conduct of the study.

- history of anaphylaxis, urticarial, or other significant adverse reaction requiring medical intervention after receipt of a vaccine. - female who is pregnant or positive in pregnancy test at screening or just prior to each vaccination administration. - female who is breast-feeding or plans to breastfeed from the time of the first vaccination through 60 days after the last vaccination. - any acute illness, as determined by the study investigator 3 days before first vaccination (these subjects can be re-scheduled). - any major surgery one month before first vaccination (these subjects can be -rescheduled). - known hiv antibody positive. - known active hepatitis b and hepatitis c disease. - previous exposure to sars-cov-2 or receipt of an investigational or licensed product for the prevention of covid-19, mers or sars. - have history of guillain-barre syndrome. - subjects who take part in another clinical study within 12 weeks prior to the day of informed consent. - immune deficiency/disorder, whether due to genetic defect, immunodeficiency disease or immunosuppressive therapy. - subjects who plan to or are undergoing anti-cancer therapy. - platelet disorder or other bleeding disorder may cause injection contraindication. - prior chronic administration of immunosuppressant or corticosteroids, cytotoxic treatment in last 6 months before first vaccination. - prior administration of immunoglobulins and/or any blood products in last 4 months before first vaccination. - receipt of any seasonal or pandemic influenza vaccine within 14 days, or any other non-study vaccine within 28 days, before study intervention administration. - anticipated receipt of any seasonal or pandemic influenza vaccine within 14 days, or any other nonstudy vaccine within 28 days, after study intervention administration. - receipt of short-term (<14 days) systemic corticosteroids. study intervention administration should be delayed until systemic corticosteroid use has been discontinued for at least 28 days. inhaled/nebulized, intra-articular, intrabursal, or topical (skin or eyes) corticosteroids are permitted. - loss or donation of blood over 500 ml within 3 months prior to screening visit or intention to donate blood or blood products for transfusion during the study. - any medical disease or condition that, in the opinion of the study investigator, may confound the results of the study or pose an additional risk to the subjects by their participation in the study. - employees at the investigator's site, of the sponsor or the contract research organization (cro) directly involved in the conduct of the study.

- history of anaphylaxis, urticarial, or other significant adverse reaction requiring medical intervention after receipt of a vaccine. - female who is pregnant or positive in pregnancy test at screening or just prior to each vaccination administration. - female who is breast-feeding or plans to breastfeed from the time of the first vaccination through 60 days after the last vaccination. - any acute illness, as determined by the study investigator 3 days before first vaccination (these subjects can be re-scheduled). - any major surgery one month before first vaccination (these subjects can be -rescheduled). - known hiv antibody positive. - known active hepatitis b and hepatitis c disease. - previous exposure to sars-cov-2 or receipt of an investigational or licensed product for the prevention of covid-19, mers or sars. - have history of guillain-barre syndrome. - subjects who take part in another clinical study within 12 weeks prior to the day of informed consent. - immune deficiency/disorder, whether due to genetic defect, immunodeficiency disease or immunosuppressive therapy. - subjects who plan to or are undergoing anti-cancer therapy. - platelet disorder or other bleeding disorder may cause injection contraindication. - prior chronic administration of immunosuppressant or corticosteroids, cytotoxic treatment in last 6 months before first vaccination. - prior administration of immunoglobulins and/or any blood products in last 4 months before first vaccination. - receipt of any seasonal or pandemic influenza vaccine within 14 days, or any other non-study vaccine within 28 days, before study intervention administration. - anticipated receipt of any seasonal or pandemic influenza vaccine within 14 days, or any other nonstudy vaccine within 28 days, after study intervention administration. - receipt of short-term (<14 days) systemic corticosteroids. study intervention administration should be delayed until systemic corticosteroid use has been discontinued for at least 28 days. inhaled/nebulized, intra-articular, intrabursal, or topical (skin or eyes) corticosteroids are permitted. - loss or donation of blood over 500 ml within 3 months prior to screening visit or intention to donate blood or blood products for transfusion during the study. - any medical disease or condition that, in the opinion of the study investigator, may confound the results of the study or pose an additional risk to the subjects by their participation in the study. - employees at the investigator's site, of the sponsor or the contract research organization (cro) directly involved in the conduct of the study.