inclusion criteria: * males and females, at least 18 years of age, capable and willing to provide informed consent; * patient must have received a diagnosis of covid-19 infection within the last 3 days; * outpatient setting (not currently hospitalized); * patient must possess at least one of the following high-risk criteria: 60 years or more of age, obesity (bmi ≥ 30 kg/m2), diabetes mellitus, uncontrolled hypertension (systolic blood pressure ≥150 mm hg), known respiratory disease (including asthma, chronic obstructive pulmonary disease, or present or past smoking), known heart failure, known coronary disease, fever of ≥38.4°c within the last 48 hours, dyspnea at the time of presentation, the combination of high neutrophil count and low lymphocyte count; * female patient is either not of childbearing potential, defined as postmenopausal for at least 1 year or surgically sterile, or is of childbearing potential and practicing at least one method of contraception and preferably two complementary forms of contraception including a barrier method (e.g. male or female condoms, spermicides, sponges, foams, jellies, diaphragm, intrauterine device (iud)) throughout the study and for 30 days after study completion; * patient or their caregiver must be able and willing to comply with the requirements of this study protocol.

inclusion criteria: * males and females, at least 18 years of age, capable and willing to provide informed consent; * patient must have received a diagnosis of covid-19 infection within the last 3 days; * outpatient setting (not currently hospitalized); * patient must possess at least one of the following high-risk criteria: 60 years or more of age, obesity (bmi ≥ 30 kg/m2), diabetes mellitus, uncontrolled hypertension (systolic blood pressure ≥150 mm hg), known respiratory disease (including asthma, chronic obstructive pulmonary disease, or present or past smoking), known heart failure, known coronary disease, fever of ≥38.4°c within the last 48 hours, dyspnea at the time of presentation, the combination of high neutrophil count and low lymphocyte count; * female patient is either not of childbearing potential, defined as postmenopausal for at least 1 year or surgically sterile, or is of childbearing potential and practicing at least one method of contraception and preferably two complementary forms of contraception including a barrier method (e.g. male or female condoms, spermicides, sponges, foams, jellies, diaphragm, intrauterine device (iud)) throughout the study and for 30 days after study completion; * patient or their caregiver must be able and willing to comply with the requirements of this study protocol.

inclusion criteria: - males and females, at least 18 years of age, capable and willing to provide informed consent; - patient must have received a diagnosis of covid-19 infection within the last 3 days; - outpatient setting (not currently hospitalized); - patient must possess at least one of the following high-risk criteria: 60 years or more of age, obesity (bmi ≥ 30 kg/m2), diabetes mellitus, uncontrolled hypertension (systolic blood pressure ≥150 mm hg), known respiratory disease (including asthma, chronic obstructive pulmonary disease, or present or past smoking), known heart failure, known coronary disease, fever of ≥38.4°c within the last 48 hours, dyspnea at the time of presentation, the combination of high neutrophil count and low lymphocyte count; - female patient is either not of childbearing potential, defined as postmenopausal for at least 1 year or surgically sterile, or is of childbearing potential and practicing at least one method of contraception and preferably two complementary forms of contraception including a barrier method (e.g. male or female condoms, spermicides, sponges, foams, jellies, diaphragm, intrauterine device (iud)) throughout the study and for 30 days after study completion; - patient or their caregiver must be able and willing to comply with the requirements of this study protocol.

inclusion criteria: - males and females, at least 18 years of age, capable and willing to provide informed consent; - patient must have received a diagnosis of covid-19 infection within the last 3 days; - outpatient setting (not currently hospitalized); - patient must possess at least one of the following high-risk criteria: 60 years or more of age, obesity (bmi ≥ 30 kg/m2), diabetes mellitus, uncontrolled hypertension (systolic blood pressure ≥150 mm hg), known respiratory disease (including asthma, chronic obstructive pulmonary disease, or present or past smoking), known heart failure, known coronary disease, fever of ≥38.4°c within the last 48 hours, dyspnea at the time of presentation, the combination of high neutrophil count and low lymphocyte count; - female patient is either not of childbearing potential, defined as postmenopausal for at least 1 year or surgically sterile, or is of childbearing potential and practicing at least one method of contraception and preferably two complementary forms of contraception including a barrier method (e.g. male or female condoms, spermicides, sponges, foams, jellies, diaphragm, intrauterine device (iud)) throughout the study and for 30 days after study completion; - patient or their caregiver must be able and willing to comply with the requirements of this study protocol.