inclusion criteria: * covid-19 patients who are admitted to the cwz with covid-19, with a laboratory confirmed sars-cov-2 infection within the previous 96 hours * respiratory failure requiring supplemental oxygen, defined as requiring supplemental oxygen to sustain an arterial po2 ≥70mmhg (measured by arterial blood gas) or an oxygen saturation of ≥94% (measured using a pulse oximeter) * at least 18 years old * able to safely swallow the study medication or possibility of safely administering this through a nasogastric tube * use of prophylactic heparin or lwmh according to hospital protocols, or use of therapeutic dosages if there is a medical indication for this * informed consent signed by patient

inclusion criteria: * covid-19 patients who are admitted to the cwz with covid-19, with a laboratory confirmed sars-cov-2 infection within the previous 96 hours * respiratory failure requiring supplemental oxygen, defined as requiring supplemental oxygen to sustain an arterial po2 ≥70mmhg (measured by arterial blood gas) or an oxygen saturation of ≥94% (measured using a pulse oximeter) * at least 18 years old * able to safely swallow the study medication or possibility of safely administering this through a nasogastric tube * use of prophylactic heparin or lwmh according to hospital protocols, or use of therapeutic dosages if there is a medical indication for this * informed consent signed by patient

inclusion criteria: - covid-19 patients who are admitted to the cwz with covid-19, with a laboratory confirmed sars-cov-2 infection within the previous 96 hours - respiratory failure requiring supplemental oxygen, defined as requiring supplemental oxygen to sustain an arterial po2 ≥70mmhg (measured by arterial blood gas) or an oxygen saturation of ≥94% (measured using a pulse oximeter) - at least 18 years old - able to safely swallow the study medication or possibility of safely administering this through a nasogastric tube - use of prophylactic heparin or lwmh according to hospital protocols, or use of therapeutic dosages if there is a medical indication for this - informed consent signed by patient

inclusion criteria: - covid-19 patients who are admitted to the cwz with covid-19, with a laboratory confirmed sars-cov-2 infection within the previous 96 hours - respiratory failure requiring supplemental oxygen, defined as requiring supplemental oxygen to sustain an arterial po2 ≥70mmhg (measured by arterial blood gas) or an oxygen saturation of ≥94% (measured using a pulse oximeter) - at least 18 years old - able to safely swallow the study medication or possibility of safely administering this through a nasogastric tube - use of prophylactic heparin or lwmh according to hospital protocols, or use of therapeutic dosages if there is a medical indication for this - informed consent signed by patient