inclusion criteria: * age: 18 years or older (including 18 years); male or female * laboratory-confirmed sars-cov-2 or covid-19 infection as determined by polymerase chain reaction (pcr) or other commercial or public health assay. * bilateral lung infection confirmed by imaging. * severe disease that meets one of the following conditions: (i) at rest, finger blood oxygen saturation ≤ 93% or pao2/fio2 ≤ 300 mmhg; (ii) requiring non-invasive or invasive mechanical ventilation; or (iii) requiring high flow oxygen ≥ 15l/min * hospitalized for no more than 5 calendar days at the time of screening

inclusion criteria: * age: 18 years or older (including 18 years); male or female * laboratory-confirmed sars-cov-2 or covid-19 infection as determined by polymerase chain reaction (pcr) or other commercial or public health assay. * bilateral lung infection confirmed by imaging. * severe disease that meets one of the following conditions: (i) at rest, finger blood oxygen saturation ≤ 93% or pao2/fio2 ≤ 300 mmhg; (ii) requiring non-invasive or invasive mechanical ventilation; or (iii) requiring high flow oxygen ≥ 15l/min * hospitalized for no more than 5 calendar days at the time of screening

inclusion criteria: - age: 18 years or older (including 18 years); male or female - laboratory-confirmed sars-cov-2 or covid-19 infection as determined by polymerase chain reaction (pcr) or other commercial or public health assay. - bilateral lung infection confirmed by imaging. - severe disease that meets one of the following conditions: (i) at rest, finger blood oxygen saturation ≤ 93% or pao2/fio2 ≤ 300 mmhg; (ii) requiring non-invasive or invasive mechanical ventilation; or (iii) requiring high flow oxygen ≥ 15l/min - hospitalized for no more than 5 calendar days at the time of screening

inclusion criteria: - age: 18 years or older (including 18 years); male or female - laboratory-confirmed sars-cov-2 or covid-19 infection as determined by polymerase chain reaction (pcr) or other commercial or public health assay. - bilateral lung infection confirmed by imaging. - severe disease that meets one of the following conditions: (i) at rest, finger blood oxygen saturation ≤ 93% or pao2/fio2 ≤ 300 mmhg; (ii) requiring non-invasive or invasive mechanical ventilation; or (iii) requiring high flow oxygen ≥ 15l/min - hospitalized for no more than 5 calendar days at the time of screening

inclusion criteria: - age: 18 years or older (including 18 years); male or female - laboratory-confirmed sars-cov-2 or covid-19 infection as determined by polymerase chain reaction (pcr) or other commercial or public health assay. - bilateral lung infection confirmed by imaging. - hospitalized patients ≥60 years old with underlying medical comorbidities or severe disease that meets one of the following conditions: (i) at rest, finger blood oxygen saturation ≤ 93% or pao2/fio2 ≤ 300 mmhg; or (ii) requiring non-invasive or invasive mechanical ventilation.

inclusion criteria: - age: 18 years or older (including 18 years); male or female - laboratory-confirmed sars-cov-2 or covid-19 infection as determined by polymerase chain reaction (pcr) or other commercial or public health assay. - bilateral lung infection confirmed by imaging. - hospitalized patients ≥60 years old with underlying medical comorbidities or severe disease that meets one of the following conditions: (i) at rest, finger blood oxygen saturation ≤ 93% or pao2/fio2 ≤ 300 mmhg; or (ii) requiring non-invasive or invasive mechanical ventilation.