inclusion criteria: 1. patients whose clinical and laboratory test results have a positive diagnosis of covid-19. 2. patients who are willing to participate as subjects in the study by signing the informed content. 3. criteria for berlin to enter ards (moderate and severe) with or without a ventilator: * pao2 / fio2: moderate 100-200 * pao2 / fio2: severe \<100 4. one or more comorbid history 5. sofa score

inclusion criteria: 1. patients whose clinical and laboratory test results have a positive diagnosis of covid-19. 2. patients who are willing to participate as subjects in the study by signing the informed content. 3. criteria for berlin to enter ards (moderate and severe) with or without a ventilator: * pao2 / fio2: moderate 100-200 * pao2 / fio2: severe \<100 4. one or more comorbid history 5. sofa score

inclusion criteria: patients whose clinical and laboratory test results have a positive diagnosis of covid-19. patients who are willing to participate as subjects in the study by signing the informed content. criteria for berlin to enter ards (moderate and severe) with or without a ventilator: pao2 / fio2: moderate 100-200 pao2 / fio2: severe <100 one or more comorbid history sofa score

inclusion criteria: patients whose clinical and laboratory test results have a positive diagnosis of covid-19. patients who are willing to participate as subjects in the study by signing the informed content. criteria for berlin to enter ards (moderate and severe) with or without a ventilator: pao2 / fio2: moderate 100-200 pao2 / fio2: severe <100 one or more comorbid history sofa score

inclusion criteria: 1. patients whose clinical and laboratory test results have a positive diagnosis of covid-19. 2. patients who are willing to participate as subjects in the study by signing the informed content. 3. criteria for berlin to enter ards (moderate and severe) with or without a ventilator: - pao2 / fio2: moderate 100-200 - pao2 / fio2: severe <100 4. one or more comorbid history 5. sofa score

inclusion criteria: 1. patients whose clinical and laboratory test results have a positive diagnosis of covid-19. 2. patients who are willing to participate as subjects in the study by signing the informed content. 3. criteria for berlin to enter ards (moderate and severe) with or without a ventilator: - pao2 / fio2: moderate 100-200 - pao2 / fio2: severe <100 4. one or more comorbid history 5. sofa score

inclusion criteria: 1. patients whose clinical and laboratory test results have a positive diagnosis of covid-19. 2. patients who are willing to participate as subjects in the study by signing the informed content. 3. criteria for berlin to enter ards (moderate and severe) with or without a ventilator: - pao2 / fio2: moderate 100-200 - pao2 / fio2: weight <100 4. one or more comorbid history 5. sofa score

inclusion criteria: 1. patients whose clinical and laboratory test results have a positive diagnosis of covid-19. 2. patients who are willing to participate as subjects in the study by signing the informed content. 3. criteria for berlin to enter ards (moderate and severe) with or without a ventilator: - pao2 / fio2: moderate 100-200 - pao2 / fio2: weight <100 4. one or more comorbid history 5. sofa score