1. malignant disease in the past five years; 2. participant with no hope of survival were clinically predicted and only received hospice care, or those who were in a deep coma and did not respond to supportive treatment measures within three hours of admission. 3. participant who are participating in other clinical trials or who have participated in other clinical trials within 3 months. 4. cases of severe shock and respiratory failure.

1. malignant disease in the past five years; 2. participant with no hope of survival were clinically predicted and only received hospice care, or those who were in a deep coma and did not respond to supportive treatment measures within three hours of admission. 3. participant who are participating in other clinical trials or who have participated in other clinical trials within 3 months. 4. cases of severe shock and respiratory failure.

malignant disease in the past five years; participant with no hope of survival were clinically predicted and only received hospice care, or those who were in a deep coma and did not respond to supportive treatment measures within three hours of admission. participant who are participating in other clinical trials or who have participated in other clinical trials within 3 months. cases of severe shock and respiratory failure.

malignant disease in the past five years; participant with no hope of survival were clinically predicted and only received hospice care, or those who were in a deep coma and did not respond to supportive treatment measures within three hours of admission. participant who are participating in other clinical trials or who have participated in other clinical trials within 3 months. cases of severe shock and respiratory failure.

1. malignant disease in the past five years; 2. participant with no hope of survival were clinically predicted and only received hospice care, or those who were in a deep coma and did not respond to supportive treatment measures within three hours of admission. 3. participant who are participating in other clinical trials or who have participated in other clinical trials within 3 months. 4. cases of severe shock and respiratory failure.

1. malignant disease in the past five years; 2. participant with no hope of survival were clinically predicted and only received hospice care, or those who were in a deep coma and did not respond to supportive treatment measures within three hours of admission. 3. participant who are participating in other clinical trials or who have participated in other clinical trials within 3 months. 4. cases of severe shock and respiratory failure.