inclusion criteria: * participants ≥18 years of age with sars-cov-2 infection confirmed by pcr before randomization * willing and able to provide written informed consent * hospitalized and requiring medical care for covid-19, (status 3 or 4 of 7-point ordinal clinical status scale) * spo2 ≥93% on room air * evidence of pulmonary infiltrate on chest x ray/and or ct scan

inclusion criteria: * participants ≥18 years of age with sars-cov-2 infection confirmed by pcr before randomization * willing and able to provide written informed consent * hospitalized and requiring medical care for covid-19, (status 3 or 4 of 7-point ordinal clinical status scale) * spo2 ≥93% on room air * evidence of pulmonary infiltrate on chest x ray/and or ct scan

inclusion criteria: - participants ≥18 years of age with sars-cov-2 infection confirmed by pcr before randomization - willing and able to provide written informed consent - hospitalized and requiring medical care for covid-19, (status 3 or 4 of 7-point ordinal clinical status scale) - spo2 ≥93% on room air - evidence of pulmonary infiltrate on chest x ray/and or ct scan

inclusion criteria: - participants ≥18 years of age with sars-cov-2 infection confirmed by pcr before randomization - willing and able to provide written informed consent - hospitalized and requiring medical care for covid-19, (status 3 or 4 of 7-point ordinal clinical status scale) - spo2 ≥93% on room air - evidence of pulmonary infiltrate on chest x ray/and or ct scan