inclusion criteria: 1. written informed consent given by the subject to participate in the trial; 2. males and females aged 18 years old and older 3. lack of covid-2019 in medical history: negative igm and igg sars cov2 antibodies enzyme-linked immunosorbent assay test result (no more than 14 days before being included in the trial) 4. negative covid-2019 pcr test result during the screening visit 5. no contact with covid-2019-infected persons within at least 14 days before being included in the trial (according to what trial subjects state); 6. negative hiv and hepatitis test results; 7. consent to use effective contraception methods during the trial 8. negative drugs or psychostimulants urine test during the screening visit; 9. negative alcohol test during the screening visit; 10. negative test for pregnancy (done for women with preserved reproductive potential) 11. no evident vaccine-induced reactions or complications after receiving immunobiological products in the person's medical history; 12. no acute infectious and/or respiratory diseases within at least 14 days before being included in the trial

inclusion criteria: 1. written informed consent given by the subject to participate in the trial; 2. males and females aged 18 years old and older 3. lack of covid-2019 in medical history: negative igm and igg sars cov2 antibodies enzyme-linked immunosorbent assay test result (no more than 14 days before being included in the trial) 4. negative covid-2019 pcr test result during the screening visit 5. no contact with covid-2019-infected persons within at least 14 days before being included in the trial (according to what trial subjects state); 6. negative hiv and hepatitis test results; 7. consent to use effective contraception methods during the trial 8. negative drugs or psychostimulants urine test during the screening visit; 9. negative alcohol test during the screening visit; 10. negative test for pregnancy (done for women with preserved reproductive potential) 11. no evident vaccine-induced reactions or complications after receiving immunobiological products in the person's medical history; 12. no acute infectious and/or respiratory diseases within at least 14 days before being included in the trial

inclusion criteria: written informed consent given by the subject to participate in the trial; males and females aged 18 years old and older lack of covid-2019 in medical history: negative igm and igg sars cov2 antibodies enzyme-linked immunosorbent assay test result (no more than 14 days before being included in the trial) negative covid-2019 pcr test result during the screening visit no contact with covid-2019-infected persons within at least 14 days before being included in the trial (according to what trial subjects state); negative hiv and hepatitis test results; consent to use effective contraception methods during the trial negative drugs or psychostimulants urine test during the screening visit; negative alcohol test during the screening visit; negative test for pregnancy (done for women with preserved reproductive potential) no evident vaccine-induced reactions or complications after receiving immunobiological products in the person's medical history; no acute infectious and/or respiratory diseases within at least 14 days before being included in the trial

inclusion criteria: written informed consent given by the subject to participate in the trial; males and females aged 18 years old and older lack of covid-2019 in medical history: negative igm and igg sars cov2 antibodies enzyme-linked immunosorbent assay test result (no more than 14 days before being included in the trial) negative covid-2019 pcr test result during the screening visit no contact with covid-2019-infected persons within at least 14 days before being included in the trial (according to what trial subjects state); negative hiv and hepatitis test results; consent to use effective contraception methods during the trial negative drugs or psychostimulants urine test during the screening visit; negative alcohol test during the screening visit; negative test for pregnancy (done for women with preserved reproductive potential) no evident vaccine-induced reactions or complications after receiving immunobiological products in the person's medical history; no acute infectious and/or respiratory diseases within at least 14 days before being included in the trial

inclusion criteria: 1. written informed consent given by the subject to participate in the trial; 2. males and females aged 18 years old and older 3. lack of covid-2019 in medical history: negative igm and igg sars cov2 antibodies enzyme-linked immunosorbent assay test result (no more than 14 days before being included in the trial) 4. negative covid-2019 pcr test result during the screening visit 5. no contact with covid-2019-infected persons within at least 14 days before being included in the trial (according to what trial subjects state); 6. negative hiv and hepatitis test results; 7. consent to use effective contraception methods during the trial 8. negative drugs or psychostimulants urine test during the screening visit; 9. negative alcohol test during the screening visit; 10. negative test for pregnancy (done for women with preserved reproductive potential) 11. no evident vaccine-induced reactions or complications after receiving immunobiological products in the person's medical history; 12. no acute infectious and/or respiratory diseases within at least 14 days before being included in the trial

inclusion criteria: 1. written informed consent given by the subject to participate in the trial; 2. males and females aged 18 years old and older 3. lack of covid-2019 in medical history: negative igm and igg sars cov2 antibodies enzyme-linked immunosorbent assay test result (no more than 14 days before being included in the trial) 4. negative covid-2019 pcr test result during the screening visit 5. no contact with covid-2019-infected persons within at least 14 days before being included in the trial (according to what trial subjects state); 6. negative hiv and hepatitis test results; 7. consent to use effective contraception methods during the trial 8. negative drugs or psychostimulants urine test during the screening visit; 9. negative alcohol test during the screening visit; 10. negative test for pregnancy (done for women with preserved reproductive potential) 11. no evident vaccine-induced reactions or complications after receiving immunobiological products in the person's medical history; 12. no acute infectious and/or respiratory diseases within at least 14 days before being included in the trial