Created at	Source	Raw Value	Validated value
Dec. 31, 2021, 5 a.m.	usa	Efficacy - Time from day of randomization to an improvement of at least two points (from the status at randomization) on severity rating (SR) scale in days	Efficacy - Time from day of randomization to an improvement of at least two points (from the status at randomization) on severity rating (SR) scale in days
Dec. 26, 2020, 12:31 a.m.	usa	Efficacy - Time from Day 1 (randomization and treatment start) to clinical change	Efficacy - Time from Day 1 (randomization and treatment start) to clinical change