* pregnancy or women who are breast feeding * two consecutive negative assays for sars-cov-2 infection * patients that lack decision-making capacity will not be approached to participate in this study * inability to tolerate oral medications * allergy or prior adverse reaction to either azithromycin or hydroxychloroquine sulfate * qtc interval \> 470 msec * history of ongoing ventricular cardiac dysrhythmias of grade 2 as described by nci ctcae 5.0 criteria * history of serious ventricular arrhythmia (vt or vf \> 3 beats in a row)

* pregnancy or women who are breast feeding * two consecutive negative assays for sars-cov-2 infection * patients that lack decision-making capacity will not be approached to participate in this study * inability to tolerate oral medications * allergy or prior adverse reaction to either azithromycin or hydroxychloroquine sulfate * qtc interval \> 470 msec * history of ongoing ventricular cardiac dysrhythmias of grade 2 as described by nci ctcae 5.0 criteria * history of serious ventricular arrhythmia (vt or vf \> 3 beats in a row)

- pregnancy or women who are breast feeding - two consecutive negative assays for sars-cov-2 infection - patients that lack decision-making capacity will not be approached to participate in this study - inability to tolerate oral medications - allergy or prior adverse reaction to either azithromycin or hydroxychloroquine sulfate - qtc interval > 470 msec - history of ongoing ventricular cardiac dysrhythmias of grade 2 as described by nci ctcae 5.0 criteria - history of serious ventricular arrhythmia (vt or vf > 3 beats in a row)

- pregnancy or women who are breast feeding - two consecutive negative assays for sars-cov-2 infection - patients that lack decision-making capacity will not be approached to participate in this study - inability to tolerate oral medications - allergy or prior adverse reaction to either azithromycin or hydroxychloroquine sulfate - qtc interval > 470 msec - history of ongoing ventricular cardiac dysrhythmias of grade 2 as described by nci ctcae 5.0 criteria - history of serious ventricular arrhythmia (vt or vf > 3 beats in a row)