inclusion criteria: individuals who: 1. are able to provide consent 2. agree to comply with all study visits and procedures 3. are willing and able to adhere to study restrictions 4. are sexually active and willing to adhere to contraceptive requirements 5. are male or female ≥18 or (in singapore) ≥21 years of age 6. are medically stable

inclusion criteria: individuals who: 1. are able to provide consent 2. agree to comply with all study visits and procedures 3. are willing and able to adhere to study restrictions 4. are sexually active and willing to adhere to contraceptive requirements 5. are male or female ≥18 or (in singapore) ≥21 years of age 6. are medically stable

inclusion criteria: individuals who: are able to provide consent agree to comply with all study visits and procedures are willing and able to adhere to study restrictions are sexually active and willing to adhere to contraceptive requirements are male or female ≥18 or (in singapore) ≥21 years of age are medically stable

inclusion criteria: individuals who: are able to provide consent agree to comply with all study visits and procedures are willing and able to adhere to study restrictions are sexually active and willing to adhere to contraceptive requirements are male or female ≥18 or (in singapore) ≥21 years of age are medically stable

inclusion criteria: individuals who: 1. are able to provide consent 2. agree to comply with all study visits and procedures 3. are willing and able to adhere to study restrictions 4. are sexually active and willing to adhere to contraceptive requirements 5. are male or female ≥18 or (in singapore) ≥21 years of age 6. are medically stable

inclusion criteria: individuals who: 1. are able to provide consent 2. agree to comply with all study visits and procedures 3. are willing and able to adhere to study restrictions 4. are sexually active and willing to adhere to contraceptive requirements 5. are male or female ≥18 or (in singapore) ≥21 years of age 6. are medically stable