inclusion criteria * adult (age ≥ 18 years) * admitted to the hospital of any participating center * confirmed sars-cov-2 infection with either: positive laboratory test for sars-cov-2\* ; or positive ct thorax diagnostic for sars-cov-2 infection according to the prevailing criteria * randomization: * within 24 hours of confirmed in-hospital sars-cov-2 infection diagnosis or * within 24 hours of hospital admission in case of pre-hospital confirmed sars-cov-2 infection. * in case there is a lack of laboratory tests for sars-cov-2 in the participating center of the potentially eligible patient, a positive laboratory test for sars-cov-2 will be no longer required. in that case, the potentially eligible patient needs to meet the prevailing criteria for the diagnosis of sars-cov-2 infection of that participating center, such as typical abnormalities on pulmonary ct in the setting of high clinical suspicion of sars-cov-2 infection.

inclusion criteria * adult (age ≥ 18 years) * admitted to the hospital of any participating center * confirmed sars-cov-2 infection with either: positive laboratory test for sars-cov-2\* ; or positive ct thorax diagnostic for sars-cov-2 infection according to the prevailing criteria * randomization: * within 24 hours of confirmed in-hospital sars-cov-2 infection diagnosis or * within 24 hours of hospital admission in case of pre-hospital confirmed sars-cov-2 infection. * in case there is a lack of laboratory tests for sars-cov-2 in the participating center of the potentially eligible patient, a positive laboratory test for sars-cov-2 will be no longer required. in that case, the potentially eligible patient needs to meet the prevailing criteria for the diagnosis of sars-cov-2 infection of that participating center, such as typical abnormalities on pulmonary ct in the setting of high clinical suspicion of sars-cov-2 infection.

inclusion criteria - adult (age ≥ 18 years) - admitted to the hospital of any participating center - confirmed sars-cov-2 infection with either: positive laboratory test for sars-cov-2* ; or positive ct thorax diagnostic for sars-cov-2 infection according to the prevailing criteria - randomization: - within 24 hours of confirmed in-hospital sars-cov-2 infection diagnosis or - within 24 hours of hospital admission in case of pre-hospital confirmed sars-cov-2 infection. - in case there is a lack of laboratory tests for sars-cov-2 in the participating center of the potentially eligible patient, a positive laboratory test for sars-cov-2 will be no longer required. in that case, the potentially eligible patient needs to meet the prevailing criteria for the diagnosis of sars-cov-2 infection of that participating center, such as typical abnormalities on pulmonary ct in the setting of high clinical suspicion of sars-cov-2 infection.

inclusion criteria - adult (age ≥ 18 years) - admitted to the hospital of any participating center - confirmed sars-cov-2 infection with either: positive laboratory test for sars-cov-2* ; or positive ct thorax diagnostic for sars-cov-2 infection according to the prevailing criteria - randomization: - within 24 hours of confirmed in-hospital sars-cov-2 infection diagnosis or - within 24 hours of hospital admission in case of pre-hospital confirmed sars-cov-2 infection. - in case there is a lack of laboratory tests for sars-cov-2 in the participating center of the potentially eligible patient, a positive laboratory test for sars-cov-2 will be no longer required. in that case, the potentially eligible patient needs to meet the prevailing criteria for the diagnosis of sars-cov-2 infection of that participating center, such as typical abnormalities on pulmonary ct in the setting of high clinical suspicion of sars-cov-2 infection.