1. known allergic reactions to components of the polio vaccine 2. febrile illness within 14 days 3. positive for sars-cov-2 antigenemia at any time prior to screening1 4. positive for sars-cov-2 antibodies at any time prior to screening1 5. subjects with fever \> 101o f at screening 6. subjects who respond yes to any of the following question: have you experienced any of the following symptoms in the past 48 hours (14): * fever or chills * cough * shortness of breath or difficulty breathing * fatigue * muscle or body aches * headache * new loss of taste or smell * sore throat * congestion or runny nose * nausea or vomiting * diarrhea 7. treatment with an investigational drug or other intervention within the 90 days prior to enrollment in this study 8. inoculation with polio vaccine within the last 12 years 9. women who are pregnant or breast feeding

1. known allergic reactions to components of the polio vaccine 2. febrile illness within 14 days 3. positive for sars-cov-2 antigenemia at any time prior to screening1 4. positive for sars-cov-2 antibodies at any time prior to screening1 5. subjects with fever \> 101o f at screening 6. subjects who respond yes to any of the following question: have you experienced any of the following symptoms in the past 48 hours (14): * fever or chills * cough * shortness of breath or difficulty breathing * fatigue * muscle or body aches * headache * new loss of taste or smell * sore throat * congestion or runny nose * nausea or vomiting * diarrhea 7. treatment with an investigational drug or other intervention within the 90 days prior to enrollment in this study 8. inoculation with polio vaccine within the last 12 years 9. women who are pregnant or breast feeding

known allergic reactions to components of the polio vaccine febrile illness within 14 days positive for sars-cov-2 antigenemia at any time prior to screening1 positive for sars-cov-2 antibodies at any time prior to screening1 subjects with fever > 101o f at screening subjects who respond yes to any of the following question: have you experienced any of the following symptoms in the past 48 hours (14): fever or chills cough shortness of breath or difficulty breathing fatigue muscle or body aches headache new loss of taste or smell sore throat congestion or runny nose nausea or vomiting diarrhea treatment with an investigational drug or other intervention within the 90 days prior to enrollment in this study inoculation with polio vaccine within the last 12 years women who are pregnant or breast feeding

known allergic reactions to components of the polio vaccine febrile illness within 14 days positive for sars-cov-2 antigenemia at any time prior to screening1 positive for sars-cov-2 antibodies at any time prior to screening1 subjects with fever > 101o f at screening subjects who respond yes to any of the following question: have you experienced any of the following symptoms in the past 48 hours (14): fever or chills cough shortness of breath or difficulty breathing fatigue muscle or body aches headache new loss of taste or smell sore throat congestion or runny nose nausea or vomiting diarrhea treatment with an investigational drug or other intervention within the 90 days prior to enrollment in this study inoculation with polio vaccine within the last 12 years women who are pregnant or breast feeding

1. known allergic reactions to components of the polio vaccine 2. febrile illness within 14 days 3. positive for sars-cov-2 antigenemia at any time prior to screening1 4. positive for sars-cov-2 antibodies at any time prior to screening1 5. subjects with fever > 101o f at screening 6. subjects who respond yes to any of the following question: have you experienced any of the following symptoms in the past 48 hours (14): - fever or chills - cough - shortness of breath or difficulty breathing - fatigue - muscle or body aches - headache - new loss of taste or smell - sore throat - congestion or runny nose - nausea or vomiting - diarrhea 7. treatment with an investigational drug or other intervention within the 90 days prior to enrollment in this study 8. inoculation with polio vaccine within the last 12 years 9. women who are pregnant or breast feeding

1. known allergic reactions to components of the polio vaccine 2. febrile illness within 14 days 3. positive for sars-cov-2 antigenemia at any time prior to screening1 4. positive for sars-cov-2 antibodies at any time prior to screening1 5. subjects with fever > 101o f at screening 6. subjects who respond yes to any of the following question: have you experienced any of the following symptoms in the past 48 hours (14): - fever or chills - cough - shortness of breath or difficulty breathing - fatigue - muscle or body aches - headache - new loss of taste or smell - sore throat - congestion or runny nose - nausea or vomiting - diarrhea 7. treatment with an investigational drug or other intervention within the 90 days prior to enrollment in this study 8. inoculation with polio vaccine within the last 12 years 9. women who are pregnant or breast feeding