inclusion criteria: * admission to the intensive care unit with severe pneumonia criteria (clinical signs of pneumonia + one of the following criteria: respiratory rate greater than 30/minute; signs of respiratory effort, sato2 \< 90% in room air); * covid-19 confirmed or highly suspicious (positive contact or suggestive image)

inclusion criteria: * admission to the intensive care unit with severe pneumonia criteria (clinical signs of pneumonia + one of the following criteria: respiratory rate greater than 30/minute; signs of respiratory effort, sato2 \< 90% in room air); * covid-19 confirmed or highly suspicious (positive contact or suggestive image)

inclusion criteria: - admission to the intensive care unit with severe pneumonia criteria (clinical signs of pneumonia + one of the following criteria: respiratory rate greater than 30/minute; signs of respiratory effort, sato2 < 90% in room air); - covid-19 confirmed or highly suspicious (positive contact or suggestive image)

inclusion criteria: - admission to the intensive care unit with severe pneumonia criteria (clinical signs of pneumonia + one of the following criteria: respiratory rate greater than 30/minute; signs of respiratory effort, sato2 < 90% in room air); - covid-19 confirmed or highly suspicious (positive contact or suggestive image)