Safety as assessed by the incidence of adverse events of special interest:;Tolerability as assessed by changes in clinical laboratory tests from baseline (Day 1);Tolerability as assessed by changes in clinical symptoms from baseline (Day 1);Tolerability as assessed by changes in vital signs from baseline (Day 1);Tolerability as assessed by changes in vital signs from baseline (Day 1);Tolerability as assessed by changes in vital signs from baseline (Day 1);Tolerability as assessed by changes in vital signs from baseline (Day 1);Tolerability as assessed by changes in clinical laboratory tests from baseline (Day 1);Tolerability as assessed by changes in clinical laboratory tests from baseline (Day 1);Tolerability as assessed by changes in vital signs from baseline (Day 1);Safety as assessed by the incidence of Treatment Emergent Adverse Events and Serious Adverse Events;Tolerability as assessed by changes in clinical laboratory tests from baseline (Day 1)

Safety as assessed by the incidence of adverse events of special interest:;Tolerability as assessed by changes in clinical laboratory tests from baseline (Day 1);Tolerability as assessed by changes in clinical symptoms from baseline (Day 1);Tolerability as assessed by changes in vital signs from baseline (Day 1);Tolerability as assessed by changes in vital signs from baseline (Day 1);Tolerability as assessed by changes in vital signs from baseline (Day 1);Tolerability as assessed by changes in vital signs from baseline (Day 1);Tolerability as assessed by changes in clinical laboratory tests from baseline (Day 1);Tolerability as assessed by changes in clinical laboratory tests from baseline (Day 1);Tolerability as assessed by changes in vital signs from baseline (Day 1);Safety as assessed by the incidence of Treatment Emergent Adverse Events and Serious Adverse Events;Tolerability as assessed by changes in clinical laboratory tests from baseline (Day 1)