1. any allergy to any composition of rhea health tone®; 2. pregnant and breastfeeding; 3. history and co-morbid of severe underlying disease where treatment and follow up is not likely to be beneficial to the patient based on physician judgment (e.g. retinopathy, cardiovascular disease (qtc \> 500 mdet (narrow qrs); qtc ≥ 550 mdet (wide qrs)), heart arrhythmia, uncontrolled diabetes mellitus, hypertension, chronic pulmonary disease, asthma, chronic kidney disease (creatinine \> 2x upper limit of normal), liver disease (sgot/sgpt \> 2x limit of normal), chronic neurological disease, or etc.). this includes people requiring care in designated supported living facilities and severe dementia; 4. possibility of being transferred to a non-study-hospital within 72 hours. 5. history of autoimmune disease, cancer, hiv aids.

1. any allergy to any composition of rhea health tone®; 2. pregnant and breastfeeding; 3. history and co-morbid of severe underlying disease where treatment and follow up is not likely to be beneficial to the patient based on physician judgment (e.g. retinopathy, cardiovascular disease (qtc \> 500 mdet (narrow qrs); qtc ≥ 550 mdet (wide qrs)), heart arrhythmia, uncontrolled diabetes mellitus, hypertension, chronic pulmonary disease, asthma, chronic kidney disease (creatinine \> 2x upper limit of normal), liver disease (sgot/sgpt \> 2x limit of normal), chronic neurological disease, or etc.). this includes people requiring care in designated supported living facilities and severe dementia; 4. possibility of being transferred to a non-study-hospital within 72 hours. 5. history of autoimmune disease, cancer, hiv aids.

any allergy to any composition of rhea health tone®; pregnant and breastfeeding; history and co-morbid of severe underlying disease where treatment and follow up is not likely to be beneficial to the patient based on physician judgment (e.g. retinopathy, cardiovascular disease (qtc > 500 mdet (narrow qrs); qtc ≥ 550 mdet (wide qrs)), heart arrhythmia, uncontrolled diabetes mellitus, hypertension, chronic pulmonary disease, asthma, chronic kidney disease (creatinine > 2x upper limit of normal), liver disease (sgot/sgpt > 2x limit of normal), chronic neurological disease, or etc.). this includes people requiring care in designated supported living facilities and severe dementia; possibility of being transferred to a non-study-hospital within 72 hours. history of autoimmune disease, cancer, hiv aids.

any allergy to any composition of rhea health tone®; pregnant and breastfeeding; history and co-morbid of severe underlying disease where treatment and follow up is not likely to be beneficial to the patient based on physician judgment (e.g. retinopathy, cardiovascular disease (qtc > 500 mdet (narrow qrs); qtc ≥ 550 mdet (wide qrs)), heart arrhythmia, uncontrolled diabetes mellitus, hypertension, chronic pulmonary disease, asthma, chronic kidney disease (creatinine > 2x upper limit of normal), liver disease (sgot/sgpt > 2x limit of normal), chronic neurological disease, or etc.). this includes people requiring care in designated supported living facilities and severe dementia; possibility of being transferred to a non-study-hospital within 72 hours. history of autoimmune disease, cancer, hiv aids.

1. any allergy to any composition of rhea health tone®; 2. pregnant and breastfeeding; 3. history and co-morbid of severe underlying disease where treatment and follow up is not likely to be beneficial to the patient based on physician judgment (e.g. retinopathy, cardiovascular disease (qtc > 500 mdet (narrow qrs); qtc ≥ 550 mdet (wide qrs)), heart arrhythmia, uncontrolled diabetes mellitus, hypertension, chronic pulmonary disease, asthma, chronic kidney disease (creatinine > 2x upper limit of normal), liver disease (sgot/sgpt > 2x limit of normal), chronic neurological disease, or etc.). this includes people requiring care in designated supported living facilities and severe dementia; 4. possibility of being transferred to a non-study-hospital within 72 hours. 5. history of autoimmune disease, cancer, hiv aids.

1. any allergy to any composition of rhea health tone®; 2. pregnant and breastfeeding; 3. history and co-morbid of severe underlying disease where treatment and follow up is not likely to be beneficial to the patient based on physician judgment (e.g. retinopathy, cardiovascular disease (qtc > 500 mdet (narrow qrs); qtc ≥ 550 mdet (wide qrs)), heart arrhythmia, uncontrolled diabetes mellitus, hypertension, chronic pulmonary disease, asthma, chronic kidney disease (creatinine > 2x upper limit of normal), liver disease (sgot/sgpt > 2x limit of normal), chronic neurological disease, or etc.). this includes people requiring care in designated supported living facilities and severe dementia; 4. possibility of being transferred to a non-study-hospital within 72 hours. 5. history of autoimmune disease, cancer, hiv aids.