1. pregnancy 2. untreated pneumothorax, which must be evaluated with a baseline chest radiograph or computerized tomography scan at least 72 hours prior to enrollment 3. presence of pneumomediastinum, pneumopericardium, significant subcutaneous emphysema, or pulmonary blebs, which should also be evaluated with a baseline chest radiograph prior to enrollment 4. current invasive mechanical ventilation 5. current non-invasive mechanical ventilation 6. any patient who will not be stable for transport to the hyperbaric chamber, in addition to any relative contraindications identified by the treating hyperbaric physician or inpatient hospital team (e.g., severely impaired cardiac output due to significant myocardial injury). 7. any patient without the capacity to provide informed consent

1. pregnancy 2. untreated pneumothorax, which must be evaluated with a baseline chest radiograph or computerized tomography scan at least 72 hours prior to enrollment 3. presence of pneumomediastinum, pneumopericardium, significant subcutaneous emphysema, or pulmonary blebs, which should also be evaluated with a baseline chest radiograph prior to enrollment 4. current invasive mechanical ventilation 5. current non-invasive mechanical ventilation 6. any patient who will not be stable for transport to the hyperbaric chamber, in addition to any relative contraindications identified by the treating hyperbaric physician or inpatient hospital team (e.g., severely impaired cardiac output due to significant myocardial injury). 7. any patient without the capacity to provide informed consent

pregnancy untreated pneumothorax, which must be evaluated with a baseline chest radiograph or computerized tomography scan at least 72 hours prior to enrollment presence of pneumomediastinum, pneumopericardium, significant subcutaneous emphysema, or pulmonary blebs, which should also be evaluated with a baseline chest radiograph prior to enrollment current invasive mechanical ventilation current non-invasive mechanical ventilation any patient who will not be stable for transport to the hyperbaric chamber, in addition to any relative contraindications identified by the treating hyperbaric physician or inpatient hospital team (e.g., severely impaired cardiac output due to significant myocardial injury). any patient without the capacity to provide informed consent

pregnancy untreated pneumothorax, which must be evaluated with a baseline chest radiograph or computerized tomography scan at least 72 hours prior to enrollment presence of pneumomediastinum, pneumopericardium, significant subcutaneous emphysema, or pulmonary blebs, which should also be evaluated with a baseline chest radiograph prior to enrollment current invasive mechanical ventilation current non-invasive mechanical ventilation any patient who will not be stable for transport to the hyperbaric chamber, in addition to any relative contraindications identified by the treating hyperbaric physician or inpatient hospital team (e.g., severely impaired cardiac output due to significant myocardial injury). any patient without the capacity to provide informed consent

1. pregnancy 2. untreated pneumothorax, which must be evaluated with a baseline chest radiograph or computerized tomography scan at least 72 hours prior to enrollment 3. presence of pneumomediastinum, pneumopericardium, significant subcutaneous emphysema, or pulmonary blebs, which should also be evaluated with a baseline chest radiograph prior to enrollment 4. current invasive mechanical ventilation 5. current non-invasive mechanical ventilation 6. any patient who will not be stable for transport to the hyperbaric chamber, in addition to any relative contraindications identified by the treating hyperbaric physician or inpatient hospital team (e.g., severely impaired cardiac output due to significant myocardial injury). 7. any patient without the capacity to provide informed consent

1. pregnancy 2. untreated pneumothorax, which must be evaluated with a baseline chest radiograph or computerized tomography scan at least 72 hours prior to enrollment 3. presence of pneumomediastinum, pneumopericardium, significant subcutaneous emphysema, or pulmonary blebs, which should also be evaluated with a baseline chest radiograph prior to enrollment 4. current invasive mechanical ventilation 5. current non-invasive mechanical ventilation 6. any patient who will not be stable for transport to the hyperbaric chamber, in addition to any relative contraindications identified by the treating hyperbaric physician or inpatient hospital team (e.g., severely impaired cardiac output due to significant myocardial injury). 7. any patient without the capacity to provide informed consent

1. pregnancy 2. untreated pneumothorax, which should be evaluated with a baseline chest radiograph or computerized tomography scan at least 72 hours prior to enrollment 3. presence of pneumomediastinum, pneumopericardium, significant subcutaneous emphysema, or pulmonary blebs, which should also be evaluated with a baseline chest radiograph prior to enrollment 4. current invasive mechanical ventilation 5. current non-invasive mechanical ventilation 6. any patient who will not be stable for transport to the hyperbaric chamber, in addition to any relative contraindications identified by the treating hyperbaric physician or inpatient hospital team (e.g., severely impaired cardiac output due to significant myocardial injury). 7. any patient without the capacity to provide informed consent

1. pregnancy 2. untreated pneumothorax, which should be evaluated with a baseline chest radiograph or computerized tomography scan at least 72 hours prior to enrollment 3. presence of pneumomediastinum, pneumopericardium, significant subcutaneous emphysema, or pulmonary blebs, which should also be evaluated with a baseline chest radiograph prior to enrollment 4. current invasive mechanical ventilation 5. current non-invasive mechanical ventilation 6. any patient who will not be stable for transport to the hyperbaric chamber, in addition to any relative contraindications identified by the treating hyperbaric physician or inpatient hospital team (e.g., severely impaired cardiac output due to significant myocardial injury). 7. any patient without the capacity to provide informed consent

1. pregnancy 2. untreated pneumothorax, which should be evaluated with a baseline chest radiograph prior to enrollment 3. presence of pneumomediastinum, pneumopericardium, significant subcutaneous emphysema, or pulmonary blebs, which should also be evaluated with a baseline chest radiograph prior to enrollment 4. intubated patients 5. patients requiring non-invasive mechanical ventilation (cpap/bipap) 6. any patient who will not be stable for transport to the hyperbaric chamber, in addition to any relative contraindications identified by the treating hyperbaric physician (e.g., severely impaired cardiac output due to significant myocardial injury). 7. any patient without the capacity to provide informed consent

1. pregnancy 2. untreated pneumothorax, which should be evaluated with a baseline chest radiograph prior to enrollment 3. presence of pneumomediastinum, pneumopericardium, significant subcutaneous emphysema, or pulmonary blebs, which should also be evaluated with a baseline chest radiograph prior to enrollment 4. intubated patients 5. patients requiring non-invasive mechanical ventilation (cpap/bipap) 6. any patient who will not be stable for transport to the hyperbaric chamber, in addition to any relative contraindications identified by the treating hyperbaric physician (e.g., severely impaired cardiac output due to significant myocardial injury). 7. any patient without the capacity to provide informed consent