* body weight under 55 kg (121 lbs) * serum creatinine level of over 1.5 mg/dl at time of randomization. * total bilirubin ≥2 mg/dl at time of randomization. * known allergy to any of the following: dimethyl sulfoxide (dmso), human serum albumin, bovine serum albumin. * stroke or acute myocardial infarction/unstable angina within 3 months prior to randomization. * chronic obstructive pulmonary disease gold stage above ii.

* body weight under 55 kg (121 lbs) * serum creatinine level of over 1.5 mg/dl at time of randomization. * total bilirubin ≥2 mg/dl at time of randomization. * known allergy to any of the following: dimethyl sulfoxide (dmso), human serum albumin, bovine serum albumin. * stroke or acute myocardial infarction/unstable angina within 3 months prior to randomization. * chronic obstructive pulmonary disease gold stage above ii.

- body weight under 55 kg (121 lbs) - serum creatinine level of over 1.5 mg/dl at time of randomization. - total bilirubin ≥2 mg/dl at time of randomization. - known allergy to any of the following: dimethyl sulfoxide (dmso), human serum albumin, bovine serum albumin. - stroke or acute myocardial infarction/unstable angina within 3 months prior to randomization. - chronic obstructive pulmonary disease gold stage above ii.

- body weight under 55 kg (121 lbs) - serum creatinine level of over 1.5 mg/dl at time of randomization. - total bilirubin ≥2 mg/dl at time of randomization. - known allergy to any of the following: dimethyl sulfoxide (dmso), human serum albumin, bovine serum albumin. - stroke or acute myocardial infarction/unstable angina within 3 months prior to randomization. - chronic obstructive pulmonary disease gold stage above ii.