inclusion criteria: * male or female patient, age \> 18 years, * laboratory (rt-pcr)-confirmed infection with sars-cov2 * diagnosis of ards according to the berlin definition of ards * under invasive, non-invasive ventilation or high-flow nasal oxygen therapy (peep ≥ 5 cmh2o) * onset of ards \<96 hours * patient with french social security system * provision of a written informed consent by the designated substitute decision maker, if present. in the event of absence, the patient can be included by investigator's decision alone.

inclusion criteria: * male or female patient, age \> 18 years, * laboratory (rt-pcr)-confirmed infection with sars-cov2 * diagnosis of ards according to the berlin definition of ards * under invasive, non-invasive ventilation or high-flow nasal oxygen therapy (peep ≥ 5 cmh2o) * onset of ards \<96 hours * patient with french social security system * provision of a written informed consent by the designated substitute decision maker, if present. in the event of absence, the patient can be included by investigator's decision alone.

inclusion criteria: - male or female patient, age > 18 years, - laboratory (rt-pcr)-confirmed infection with sars-cov2 - diagnosis of ards according to the berlin definition of ards - under invasive, non-invasive ventilation or high-flow nasal oxygen therapy (peep ≥ 5 cmh2o) - onset of ards <96 hours - patient with french social security system - provision of a written informed consent by the designated substitute decision maker, if present. in the event of absence, the patient can be included by investigator's decision alone.

inclusion criteria: - male or female patient, age > 18 years, - laboratory (rt-pcr)-confirmed infection with sars-cov2 - diagnosis of ards according to the berlin definition of ards - under invasive, non-invasive ventilation or high-flow nasal oxygen therapy (peep ≥ 5 cmh2o) - onset of ards <96 hours - patient with french social security system - provision of a written informed consent by the designated substitute decision maker, if present. in the event of absence, the patient can be included by investigator's decision alone.