inclusion criteria: * written informed consaent obtained * hospitalized with covid-19 disease * age \>/= 18 years * sars cov-2 nho posit * sp=2 \</93% on ambient air or respiratory rate \>30 /min * any 2 of the 4: p-il-6 \> 2 x uln / p-ferritin \> 2 x uln / p-fidd \>1.5 mg/l / p- crp \>40 mg/l without obvious presence of bacterial infection (normal values: p -il-6 \<5.9 ng/l; p-ferritin, men 30-400 mikrog/l, women 13-150 mikrog/l ; p-fidd (fibrin degradation products, d-dimer) \<0.5 mg/l; p-crp \<10 mg/l)

inclusion criteria: * written informed consaent obtained * hospitalized with covid-19 disease * age \>/= 18 years * sars cov-2 nho posit * sp=2 \</93% on ambient air or respiratory rate \>30 /min * any 2 of the 4: p-il-6 \> 2 x uln / p-ferritin \> 2 x uln / p-fidd \>1.5 mg/l / p- crp \>40 mg/l without obvious presence of bacterial infection (normal values: p -il-6 \<5.9 ng/l; p-ferritin, men 30-400 mikrog/l, women 13-150 mikrog/l ; p-fidd (fibrin degradation products, d-dimer) \<0.5 mg/l; p-crp \<10 mg/l)

inclusion criteria: - written informed consaent obtained - hospitalized with covid-19 disease - age >/= 18 years - sars cov-2 nho posit - sp=2 </93% on ambient air or respiratory rate >30 /min - any 2 of the 4: p-il-6 > 2 x uln / p-ferritin > 2 x uln / p-fidd >1.5 mg/l / p- crp >40 mg/l without obvious presence of bacterial infection (normal values: p -il-6 <5.9 ng/l; p-ferritin, men 30-400 mikrog/l, women 13-150 mikrog/l ; p-fidd (fibrin degradation products, d-dimer) <0.5 mg/l; p-crp <10 mg/l)

inclusion criteria: - written informed consaent obtained - hospitalized with covid-19 disease - age >/= 18 years - sars cov-2 nho posit - sp=2 </93% on ambient air or respiratory rate >30 /min - any 2 of the 4: p-il-6 > 2 x uln / p-ferritin > 2 x uln / p-fidd >1.5 mg/l / p- crp >40 mg/l without obvious presence of bacterial infection (normal values: p -il-6 <5.9 ng/l; p-ferritin, men 30-400 mikrog/l, women 13-150 mikrog/l ; p-fidd (fibrin degradation products, d-dimer) <0.5 mg/l; p-crp <10 mg/l)