inclusion criteria: 1. male or female subjects at least 18 years of age. 2. ability to understand and the willingness to sign a written informed consent. 3. laboratory-confirmed sars-cov-2 infection as determined by a positive pcr test documented prior to randomization 4. requirement for intensive inpatient hospital care 5. acute hypoxemic respiratory failure typifying ards 6. adequate liver function 7. use of effective contraception

inclusion criteria: 1. male or female subjects at least 18 years of age. 2. ability to understand and the willingness to sign a written informed consent. 3. laboratory-confirmed sars-cov-2 infection as determined by a positive pcr test documented prior to randomization 4. requirement for intensive inpatient hospital care 5. acute hypoxemic respiratory failure typifying ards 6. adequate liver function 7. use of effective contraception

inclusion criteria: male or female subjects at least 18 years of age. ability to understand and the willingness to sign a written informed consent. laboratory-confirmed sars-cov-2 infection as determined by a positive pcr test documented prior to randomization requirement for intensive inpatient hospital care acute hypoxemic respiratory failure typifying ards adequate liver function use of effective contraception

inclusion criteria: male or female subjects at least 18 years of age. ability to understand and the willingness to sign a written informed consent. laboratory-confirmed sars-cov-2 infection as determined by a positive pcr test documented prior to randomization requirement for intensive inpatient hospital care acute hypoxemic respiratory failure typifying ards adequate liver function use of effective contraception

inclusion criteria: 1. male or female subjects at least 18 years of age. 2. ability to understand and the willingness to sign a written informed consent. 3. laboratory-confirmed sars-cov-2 infection as determined by a positive pcr test documented prior to randomization 4. requirement for intensive inpatient hospital care 5. acute hypoxemic respiratory failure typifying ards 6. adequate liver function 7. use of effective contraception

inclusion criteria: 1. male or female subjects at least 18 years of age. 2. ability to understand and the willingness to sign a written informed consent. 3. laboratory-confirmed sars-cov-2 infection as determined by a positive pcr test documented prior to randomization 4. requirement for intensive inpatient hospital care 5. acute hypoxemic respiratory failure typifying ards 6. adequate liver function 7. use of effective contraception

inclusion criteria: male or female subjects at least 18 years of age. ability to understand and the willingness to sign a written informed consent. laboratory-confirmed sars-cov-2 infection as determined by a positive pcr test documented prior to randomization requirement for intensive inpatient hospital care acute hypoxemic respiratory failure typifying ards adequate liver function use of effective contraception

inclusion criteria: male or female subjects at least 18 years of age. ability to understand and the willingness to sign a written informed consent. laboratory-confirmed sars-cov-2 infection as determined by a positive pcr test documented prior to randomization requirement for intensive inpatient hospital care acute hypoxemic respiratory failure typifying ards adequate liver function use of effective contraception

inclusion criteria: 1. male or female subjects at least 18 years of age. 2. ability to understand and the willingness to sign a written informed consent. 3. laboratory-confirmed sars-cov-2 infection as determined by a positive pcr test documented prior to randomization 4. requirement for intensive inpatient hospital care 5. acute hypoxemic respiratory failure typifying ards 6. adequate liver function 7. use of effective contraception

inclusion criteria: 1. male or female subjects at least 18 years of age. 2. ability to understand and the willingness to sign a written informed consent. 3. laboratory-confirmed sars-cov-2 infection as determined by a positive pcr test documented prior to randomization 4. requirement for intensive inpatient hospital care 5. acute hypoxemic respiratory failure typifying ards 6. adequate liver function 7. use of effective contraception