* negative result of rt-pcr for sars-cov2 collected on admission * impossibility to use oral medications * history of severe liver disease (child pugh c class) * previous renal failure * severe heart failure (nyha 3 or 4) * copd (gold 3 and 4) * neoplasia in the last 5 years * known autoimmune disease * individuals with known hypersensitivity to study drug * previous treatment with the study medication during the last 30 days * clinical suspicion of tuberculosis and bacterial pneumonia

* negative result of rt-pcr for sars-cov2 collected on admission * impossibility to use oral medications * history of severe liver disease (child pugh c class) * previous renal failure * severe heart failure (nyha 3 or 4) * copd (gold 3 and 4) * neoplasia in the last 5 years * known autoimmune disease * individuals with known hypersensitivity to study drug * previous treatment with the study medication during the last 30 days * clinical suspicion of tuberculosis and bacterial pneumonia

- negative result of rt-pcr for sars-cov2 collected on admission - impossibility to use oral medications - history of severe liver disease (child pugh c class) - previous renal failure - severe heart failure (nyha 3 or 4) - copd (gold 3 and 4) - neoplasia in the last 5 years - known autoimmune disease - individuals with known hypersensitivity to study drug - previous treatment with the study medication during the last 30 days - clinical suspicion of tuberculosis and bacterial pneumonia

- negative result of rt-pcr for sars-cov2 collected on admission - impossibility to use oral medications - history of severe liver disease (child pugh c class) - previous renal failure - severe heart failure (nyha 3 or 4) - copd (gold 3 and 4) - neoplasia in the last 5 years - known autoimmune disease - individuals with known hypersensitivity to study drug - previous treatment with the study medication during the last 30 days - clinical suspicion of tuberculosis and bacterial pneumonia