Created at Source Raw Value Validated value
June 25, 2024, noon usa

1. hypersensitivity to favipiravir and/or other components of the study drug. 2. impossibility of ct procedure (for example, gypsum dressing or metal structures in the field of imaging). 3. the need to use drugs from the list of prohibited therapy. 4. need for treatment in the intensive care unit. 5. impaired liver function (ast and/or alt ≥ 2 unl and/or total bilirubin ≥ 1.5 unl) at the time of screening. 6. impaired kidney function (creatinine clearance according to cockcroft-gault formula less than 45 ml/min) at the time of screening. 7. positive testing for hiv, syphilis, hepatitis b and/or c. 8. chronic heart failure fc iii-iv according to new york heart association (nyha) functional classification. 9. malabsorption syndrome or other clinically significant gastrointestinal disease that may affect absorption of the study drug (non-correctable vomiting, diarrhea, ulcerative colitis, and others). 10. malignancies in the past medical history. 11. alcohol, pharmacological and/or drug addiction in the past medical history and/or at the time of screening. 12. schizophrenia, schizoaffective disorder, bipolar disorder, or other history of mental pathology or suspicion of their presence at the time of screening. 13. severe, decompensated or unstable somatic diseases (any disease or condition that threaten the patient's life or impair the patient's prognosis, and also make it impossible for him/her to participate in the clinical study). 14. any history data that the investigating physician believes could lead to complication in the interpretation of the study results or create an additional risk to the patient as a result of his/her participation in the study. 15. patient's unwillingness or inability to comply with procedures of the study protocol (in the opinion of physician investigator). 16. pregnant or nursing women or women planning pregnancy. 17. participation in another clinical study for 3 months prior to inclusion in the study. 18. other conditions that, according to the physician investigator, prevent the patient from being included in the study.

1. hypersensitivity to favipiravir and/or other components of the study drug. 2. impossibility of ct procedure (for example, gypsum dressing or metal structures in the field of imaging). 3. the need to use drugs from the list of prohibited therapy. 4. need for treatment in the intensive care unit. 5. impaired liver function (ast and/or alt ≥ 2 unl and/or total bilirubin ≥ 1.5 unl) at the time of screening. 6. impaired kidney function (creatinine clearance according to cockcroft-gault formula less than 45 ml/min) at the time of screening. 7. positive testing for hiv, syphilis, hepatitis b and/or c. 8. chronic heart failure fc iii-iv according to new york heart association (nyha) functional classification. 9. malabsorption syndrome or other clinically significant gastrointestinal disease that may affect absorption of the study drug (non-correctable vomiting, diarrhea, ulcerative colitis, and others). 10. malignancies in the past medical history. 11. alcohol, pharmacological and/or drug addiction in the past medical history and/or at the time of screening. 12. schizophrenia, schizoaffective disorder, bipolar disorder, or other history of mental pathology or suspicion of their presence at the time of screening. 13. severe, decompensated or unstable somatic diseases (any disease or condition that threaten the patient's life or impair the patient's prognosis, and also make it impossible for him/her to participate in the clinical study). 14. any history data that the investigating physician believes could lead to complication in the interpretation of the study results or create an additional risk to the patient as a result of his/her participation in the study. 15. patient's unwillingness or inability to comply with procedures of the study protocol (in the opinion of physician investigator). 16. pregnant or nursing women or women planning pregnancy. 17. participation in another clinical study for 3 months prior to inclusion in the study. 18. other conditions that, according to the physician investigator, prevent the patient from being included in the study.

Nov. 16, 2021, 6:30 p.m. usa

hypersensitivity to favipiravir and/or other components of the study drug. impossibility of ct procedure (for example, gypsum dressing or metal structures in the field of imaging). the need to use drugs from the list of prohibited therapy. need for treatment in the intensive care unit. impaired liver function (ast and/or alt ≥ 2 unl and/or total bilirubin ≥ 1.5 unl) at the time of screening. impaired kidney function (creatinine clearance according to cockcroft-gault formula less than 45 ml/min) at the time of screening. positive testing for hiv, syphilis, hepatitis b and/or c. chronic heart failure fc iii-iv according to new york heart association (nyha) functional classification. malabsorption syndrome or other clinically significant gastrointestinal disease that may affect absorption of the study drug (non-correctable vomiting, diarrhea, ulcerative colitis, and others). malignancies in the past medical history. alcohol, pharmacological and/or drug addiction in the past medical history and/or at the time of screening. schizophrenia, schizoaffective disorder, bipolar disorder, or other history of mental pathology or suspicion of their presence at the time of screening. severe, decompensated or unstable somatic diseases (any disease or condition that threaten the patient's life or impair the patient's prognosis, and also make it impossible for him/her to participate in the clinical study). any history data that the investigating physician believes could lead to complication in the interpretation of the study results or create an additional risk to the patient as a result of his/her participation in the study. patient's unwillingness or inability to comply with procedures of the study protocol (in the opinion of physician investigator). pregnant or nursing women or women planning pregnancy. participation in another clinical study for 3 months prior to inclusion in the study. other conditions that, according to the physician investigator, prevent the patient from being included in the study.

hypersensitivity to favipiravir and/or other components of the study drug. impossibility of ct procedure (for example, gypsum dressing or metal structures in the field of imaging). the need to use drugs from the list of prohibited therapy. need for treatment in the intensive care unit. impaired liver function (ast and/or alt ≥ 2 unl and/or total bilirubin ≥ 1.5 unl) at the time of screening. impaired kidney function (creatinine clearance according to cockcroft-gault formula less than 45 ml/min) at the time of screening. positive testing for hiv, syphilis, hepatitis b and/or c. chronic heart failure fc iii-iv according to new york heart association (nyha) functional classification. malabsorption syndrome or other clinically significant gastrointestinal disease that may affect absorption of the study drug (non-correctable vomiting, diarrhea, ulcerative colitis, and others). malignancies in the past medical history. alcohol, pharmacological and/or drug addiction in the past medical history and/or at the time of screening. schizophrenia, schizoaffective disorder, bipolar disorder, or other history of mental pathology or suspicion of their presence at the time of screening. severe, decompensated or unstable somatic diseases (any disease or condition that threaten the patient's life or impair the patient's prognosis, and also make it impossible for him/her to participate in the clinical study). any history data that the investigating physician believes could lead to complication in the interpretation of the study results or create an additional risk to the patient as a result of his/her participation in the study. patient's unwillingness or inability to comply with procedures of the study protocol (in the opinion of physician investigator). pregnant or nursing women or women planning pregnancy. participation in another clinical study for 3 months prior to inclusion in the study. other conditions that, according to the physician investigator, prevent the patient from being included in the study.

Oct. 26, 2020, 11:31 p.m. usa

1. hypersensitivity to favipiravir and/or other components of the study drug. 2. impossibility of ct procedure (for example, gypsum dressing or metal structures in the field of imaging). 3. the need to use drugs from the list of prohibited therapy. 4. need for treatment in the intensive care unit. 5. impaired liver function (ast and/or alt ≥ 2 unl and/or total bilirubin ≥ 1.5 unl) at the time of screening. 6. impaired kidney function (creatinine clearance according to cockcroft-gault formula less than 45 ml/min) at the time of screening. 7. positive testing for hiv, syphilis, hepatitis b and/or c. 8. chronic heart failure fc iii-iv according to new york heart association (nyha) functional classification. 9. malabsorption syndrome or other clinically significant gastrointestinal disease that may affect absorption of the study drug (non-correctable vomiting, diarrhea, ulcerative colitis, and others). 10. malignancies in the past medical history. 11. alcohol, pharmacological and/or drug addiction in the past medical history and/or at the time of screening. 12. schizophrenia, schizoaffective disorder, bipolar disorder, or other history of mental pathology or suspicion of their presence at the time of screening. 13. severe, decompensated or unstable somatic diseases (any disease or condition that threaten the patient's life or impair the patient's prognosis, and also make it impossible for him/her to participate in the clinical study). 14. any history data that the investigating physician believes could lead to complication in the interpretation of the study results or create an additional risk to the patient as a result of his/her participation in the study. 15. patient's unwillingness or inability to comply with procedures of the study protocol (in the opinion of physician investigator). 16. pregnant or nursing women or women planning pregnancy. 17. participation in another clinical study for 3 months prior to inclusion in the study. 18. other conditions that, according to the physician investigator, prevent the patient from being included in the study.

1. hypersensitivity to favipiravir and/or other components of the study drug. 2. impossibility of ct procedure (for example, gypsum dressing or metal structures in the field of imaging). 3. the need to use drugs from the list of prohibited therapy. 4. need for treatment in the intensive care unit. 5. impaired liver function (ast and/or alt ≥ 2 unl and/or total bilirubin ≥ 1.5 unl) at the time of screening. 6. impaired kidney function (creatinine clearance according to cockcroft-gault formula less than 45 ml/min) at the time of screening. 7. positive testing for hiv, syphilis, hepatitis b and/or c. 8. chronic heart failure fc iii-iv according to new york heart association (nyha) functional classification. 9. malabsorption syndrome or other clinically significant gastrointestinal disease that may affect absorption of the study drug (non-correctable vomiting, diarrhea, ulcerative colitis, and others). 10. malignancies in the past medical history. 11. alcohol, pharmacological and/or drug addiction in the past medical history and/or at the time of screening. 12. schizophrenia, schizoaffective disorder, bipolar disorder, or other history of mental pathology or suspicion of their presence at the time of screening. 13. severe, decompensated or unstable somatic diseases (any disease or condition that threaten the patient's life or impair the patient's prognosis, and also make it impossible for him/her to participate in the clinical study). 14. any history data that the investigating physician believes could lead to complication in the interpretation of the study results or create an additional risk to the patient as a result of his/her participation in the study. 15. patient's unwillingness or inability to comply with procedures of the study protocol (in the opinion of physician investigator). 16. pregnant or nursing women or women planning pregnancy. 17. participation in another clinical study for 3 months prior to inclusion in the study. 18. other conditions that, according to the physician investigator, prevent the patient from being included in the study.