inclusion criteria: 1. adults aged 18 years and older, body mass index (bmi) is between 18-30, able to provide legal proof of identity 2. participants voluntarily agreed to participate in the study and signed an informed consent form 3. the subject has the ability to understand the study process and is willing and able to comply with all study proposals and other requirements of the study 4. be willing and able to comply with protocol and complete 12-month study follow-up 5. have received 2 doses of inactivated sars-cov-2 vaccine for 6 months and less than 12 months before enrollment 6. male and female subjects of childbearing age agree to use effective contraception from screening period until 12 months after vaccination; female subjects of childbearing age have taken effective contraceptive measures 1 month before enrollment 7. female subjects of childbearing age are not at pregnant period (negative result of pregnancy test) or lactation period 8. male and female subjects of child-bearing age agree that do not donate eggs (eggs, oocytes) for assisted reproduction (female subjects of reproductive age) or avoid sperm donation (male subjects) from screening period until 12 months after vaccination

inclusion criteria: 1. adults aged 18 years and older, body mass index (bmi) is between 18-30, able to provide legal proof of identity 2. participants voluntarily agreed to participate in the study and signed an informed consent form 3. the subject has the ability to understand the study process and is willing and able to comply with all study proposals and other requirements of the study 4. be willing and able to comply with protocol and complete 12-month study follow-up 5. have received 2 doses of inactivated sars-cov-2 vaccine for 6 months and less than 12 months before enrollment 6. male and female subjects of childbearing age agree to use effective contraception from screening period until 12 months after vaccination; female subjects of childbearing age have taken effective contraceptive measures 1 month before enrollment 7. female subjects of childbearing age are not at pregnant period (negative result of pregnancy test) or lactation period 8. male and female subjects of child-bearing age agree that do not donate eggs (eggs, oocytes) for assisted reproduction (female subjects of reproductive age) or avoid sperm donation (male subjects) from screening period until 12 months after vaccination

inclusion criteria: adults aged 18 years and older, body mass index (bmi) is between 18-30, able to provide legal proof of identity participants voluntarily agreed to participate in the study and signed an informed consent form the subject has the ability to understand the study process and is willing and able to comply with all study proposals and other requirements of the study be willing and able to comply with protocol and complete 12-month study follow-up have received 2 doses of inactivated sars-cov-2 vaccine for 6 months and less than 12 months before enrollment male and female subjects of childbearing age agree to use effective contraception from screening period until 12 months after vaccination; female subjects of childbearing age have taken effective contraceptive measures 1 month before enrollment female subjects of childbearing age are not at pregnant period (negative result of pregnancy test) or lactation period male and female subjects of child-bearing age agree that do not donate eggs (eggs, oocytes) for assisted reproduction (female subjects of reproductive age) or avoid sperm donation (male subjects) from screening period until 12 months after vaccination

inclusion criteria: adults aged 18 years and older, body mass index (bmi) is between 18-30, able to provide legal proof of identity participants voluntarily agreed to participate in the study and signed an informed consent form the subject has the ability to understand the study process and is willing and able to comply with all study proposals and other requirements of the study be willing and able to comply with protocol and complete 12-month study follow-up have received 2 doses of inactivated sars-cov-2 vaccine for 6 months and less than 12 months before enrollment male and female subjects of childbearing age agree to use effective contraception from screening period until 12 months after vaccination; female subjects of childbearing age have taken effective contraceptive measures 1 month before enrollment female subjects of childbearing age are not at pregnant period (negative result of pregnancy test) or lactation period male and female subjects of child-bearing age agree that do not donate eggs (eggs, oocytes) for assisted reproduction (female subjects of reproductive age) or avoid sperm donation (male subjects) from screening period until 12 months after vaccination