\[current disease and medical history\] 1. subject who has identified any acute, chronic, or clinically significant disease as a result of a physical or laboratory examination during a screening visit (visit 1) 2. subject who has a history of malignant tumors within the past 5 years 3. subject who has an immune dysfunction, including immunodeficiency disease, or a family history thereof through a medical history and/or physical examination 4. subject who has positive sars-cov-2 igg ab results during screening visit (visit 1) 5. subject previously diagnosed with covid-19 6. subject with any acute, chronic, or clinically significant disease as a result of physical examination or laboratory examination at the screening visit (visit 1) 7. subject with a history of malignancy within 5 years before the first dose of the investigational drug (except for basal cell and squamous cell carcinoma of the skin) 8. subject with immune dysfunction including immunodeficiency disease through medical history and/or physical examination, or with a family history 9. subject with a positive result of virus test (hepatitis b test, hepatitis a test, human immunodeficiency virus test, hepatitis c test) at the screening visit (visit 1) 10. subject who are significantly abnormal clinically in laboratory tests, electrocardiogram, chest, and x-rays performed at the screening visit (visit 1) and those who are judged impossible to participate in the clinical trial at the discretion of the investigator 11. subject with a history of hypersensitivity or severe allergic reaction to vaccine administration \[e.g. anaphylaxis, guillain-barre syndrome, urticaria\*, other clinically significant reactions requiring medical intervention\] 12. urticaria: those with a history of systemic urticaria within 5 years before administration of investigational drugs 13. subject with diseases on such systems as hepatobiliary, kidney, nervous system (central or peripheral), respiratory (asthma, pneumonia, etc.), endocrine (uncontrolled diabetes mellitus, hyperlipidemia, etc.), cardiovascular (congestive heart failure, coronary artery disease, myocardial infarction, uncontrolled hypertension) etc.), urinary, psychiatric, musculoskeletal disorders or have a clinically significant history that it is judged to be unable to participate in a clinical trial under the judgment of the investigator 14. subject with autoimmune diseases including autoimmune hypothyroidism and psoriasis 15. subject with suspected or history of alcohol or substance abuse 12 months prior to the scheduled screening visit (visit 1). alcohol abuse standards are defined as follows: 16. subject who has had a serious adverse reaction to a drug containing the same component as the investigational drug or has a history of allergy 17. subject who has had a cough, dyspnea, chills, muscle pain, headache, sore throat, loss of smell or taste and an acute fever in which the body temperature exceeds 37.5°c within 72 hours prior to administration of the clinical trial drug 18. subject who has been diagnosed with covid-19 and/or have been confirmed or treated for covid-19 infection as a result of laboratory tests 19. subject with a history of previous mers-cov or sars-cov infection 20. subject with a history of hereditary or idiopathic angioneurotic edema 21. subject with a history of organ or bone marrow transplantation \[relating to contraindicated drugs\] 22. subject who has experience in administering an immunosuppressant or immune modifying drug within 6 months prior to administration of an investigational drug 23. patients with hemophilia who are at risk of serious bleeding when injected intramuscularly or are taking anticoagulants. 24. subject who has received immunoglobulin or blood-derived products within 3 months prior to administration of the investigational drug or are expected to administer it during the clinical trial period 25. subject who participated in other clinical trials similar to the investigational drug before the screening visit (visit 1) 26. subject with a history of mers-cov or sars-cov vaccination 27. subject who haa received or plan to administer the vaccine within 4 weeks before/after administration of this investigational drug 28. subject with a history of platelet-related disease or hemorrhagic disease, a history of severe bleeding or bruising after intramuscular injection or venipuncture or a person taking anticoagulants 29. if there is a history of dependent administration of psychotropic drugs or narcotic analgesics within 6 months prior to administration of the investigational drug or in case of a mental illness or social condition in which it is difficult to comply with the clinical trial procedure according to the judgment of the investigator

\[current disease and medical history\] 1. subject who has identified any acute, chronic, or clinically significant disease as a result of a physical or laboratory examination during a screening visit (visit 1) 2. subject who has a history of malignant tumors within the past 5 years 3. subject who has an immune dysfunction, including immunodeficiency disease, or a family history thereof through a medical history and/or physical examination 4. subject who has positive sars-cov-2 igg ab results during screening visit (visit 1) 5. subject previously diagnosed with covid-19 6. subject with any acute, chronic, or clinically significant disease as a result of physical examination or laboratory examination at the screening visit (visit 1) 7. subject with a history of malignancy within 5 years before the first dose of the investigational drug (except for basal cell and squamous cell carcinoma of the skin) 8. subject with immune dysfunction including immunodeficiency disease through medical history and/or physical examination, or with a family history 9. subject with a positive result of virus test (hepatitis b test, hepatitis a test, human immunodeficiency virus test, hepatitis c test) at the screening visit (visit 1) 10. subject who are significantly abnormal clinically in laboratory tests, electrocardiogram, chest, and x-rays performed at the screening visit (visit 1) and those who are judged impossible to participate in the clinical trial at the discretion of the investigator 11. subject with a history of hypersensitivity or severe allergic reaction to vaccine administration \[e.g. anaphylaxis, guillain-barre syndrome, urticaria\*, other clinically significant reactions requiring medical intervention\] 12. urticaria: those with a history of systemic urticaria within 5 years before administration of investigational drugs 13. subject with diseases on such systems as hepatobiliary, kidney, nervous system (central or peripheral), respiratory (asthma, pneumonia, etc.), endocrine (uncontrolled diabetes mellitus, hyperlipidemia, etc.), cardiovascular (congestive heart failure, coronary artery disease, myocardial infarction, uncontrolled hypertension) etc.), urinary, psychiatric, musculoskeletal disorders or have a clinically significant history that it is judged to be unable to participate in a clinical trial under the judgment of the investigator 14. subject with autoimmune diseases including autoimmune hypothyroidism and psoriasis 15. subject with suspected or history of alcohol or substance abuse 12 months prior to the scheduled screening visit (visit 1). alcohol abuse standards are defined as follows: 16. subject who has had a serious adverse reaction to a drug containing the same component as the investigational drug or has a history of allergy 17. subject who has had a cough, dyspnea, chills, muscle pain, headache, sore throat, loss of smell or taste and an acute fever in which the body temperature exceeds 37.5°c within 72 hours prior to administration of the clinical trial drug 18. subject who has been diagnosed with covid-19 and/or have been confirmed or treated for covid-19 infection as a result of laboratory tests 19. subject with a history of previous mers-cov or sars-cov infection 20. subject with a history of hereditary or idiopathic angioneurotic edema 21. subject with a history of organ or bone marrow transplantation \[relating to contraindicated drugs\] 22. subject who has experience in administering an immunosuppressant or immune modifying drug within 6 months prior to administration of an investigational drug 23. patients with hemophilia who are at risk of serious bleeding when injected intramuscularly or are taking anticoagulants. 24. subject who has received immunoglobulin or blood-derived products within 3 months prior to administration of the investigational drug or are expected to administer it during the clinical trial period 25. subject who participated in other clinical trials similar to the investigational drug before the screening visit (visit 1) 26. subject with a history of mers-cov or sars-cov vaccination 27. subject who haa received or plan to administer the vaccine within 4 weeks before/after administration of this investigational drug 28. subject with a history of platelet-related disease or hemorrhagic disease, a history of severe bleeding or bruising after intramuscular injection or venipuncture or a person taking anticoagulants 29. if there is a history of dependent administration of psychotropic drugs or narcotic analgesics within 6 months prior to administration of the investigational drug or in case of a mental illness or social condition in which it is difficult to comply with the clinical trial procedure according to the judgment of the investigator

[current disease and medical history] subject who has identified any acute, chronic, or clinically significant disease as a result of a physical or laboratory examination during a screening visit (visit 1) subject who has a history of malignant tumors within the past 5 years subject who has an immune dysfunction, including immunodeficiency disease, or a family history thereof through a medical history and/or physical examination subject who has positive sars-cov-2 igg ab results during screening visit (visit 1) subject previously diagnosed with covid-19 subject with any acute, chronic, or clinically significant disease as a result of physical examination or laboratory examination at the screening visit (visit 1) subject with a history of malignancy within 5 years before the first dose of the investigational drug (except for basal cell and squamous cell carcinoma of the skin) subject with immune dysfunction including immunodeficiency disease through medical history and/or physical examination, or with a family history subject with a positive result of virus test (hepatitis b test, hepatitis a test, human immunodeficiency virus test, hepatitis c test) at the screening visit (visit 1) subject who are significantly abnormal clinically in laboratory tests, electrocardiogram, chest, and x-rays performed at the screening visit (visit 1) and those who are judged impossible to participate in the clinical trial at the discretion of the investigator subject with a history of hypersensitivity or severe allergic reaction to vaccine administration [e.g. anaphylaxis, guillain-barre syndrome, urticaria*, other clinically significant reactions requiring medical intervention] urticaria: those with a history of systemic urticaria within 5 years before administration of investigational drugs subject with diseases on such systems as hepatobiliary, kidney, nervous system (central or peripheral), respiratory (asthma, pneumonia, etc.), endocrine (uncontrolled diabetes mellitus, hyperlipidemia, etc.), cardiovascular (congestive heart failure, coronary artery disease, myocardial infarction, uncontrolled hypertension) etc.), urinary, psychiatric, musculoskeletal disorders or have a clinically significant history that it is judged to be unable to participate in a clinical trial under the judgment of the investigator subject with autoimmune diseases including autoimmune hypothyroidism and psoriasis subject with suspected or history of alcohol or substance abuse 12 months prior to the scheduled screening visit (visit 1). alcohol abuse standards are defined as follows: subject who has had a serious adverse reaction to a drug containing the same component as the investigational drug or has a history of allergy subject who has had a cough, dyspnea, chills, muscle pain, headache, sore throat, loss of smell or taste and an acute fever in which the body temperature exceeds 37.5°c within 72 hours prior to administration of the clinical trial drug subject who has been diagnosed with covid-19 and/or have been confirmed or treated for covid-19 infection as a result of laboratory tests subject with a history of previous mers-cov or sars-cov infection subject with a history of hereditary or idiopathic angioneurotic edema subject with a history of organ or bone marrow transplantation [relating to contraindicated drugs] subject who has experience in administering an immunosuppressant or immune modifying drug within 6 months prior to administration of an investigational drug patients with hemophilia who are at risk of serious bleeding when injected intramuscularly or are taking anticoagulants. subject who has received immunoglobulin or blood-derived products within 3 months prior to administration of the investigational drug or are expected to administer it during the clinical trial period subject who participated in other clinical trials similar to the investigational drug before the screening visit (visit 1) subject with a history of mers-cov or sars-cov vaccination subject who haa received or plan to administer the vaccine within 4 weeks before/after administration of this investigational drug subject with a history of platelet-related disease or hemorrhagic disease, a history of severe bleeding or bruising after intramuscular injection or venipuncture or a person taking anticoagulants if there is a history of dependent administration of psychotropic drugs or narcotic analgesics within 6 months prior to administration of the investigational drug or in case of a mental illness or social condition in which it is difficult to comply with the clinical trial procedure according to the judgment of the investigator

[current disease and medical history] subject who has identified any acute, chronic, or clinically significant disease as a result of a physical or laboratory examination during a screening visit (visit 1) subject who has a history of malignant tumors within the past 5 years subject who has an immune dysfunction, including immunodeficiency disease, or a family history thereof through a medical history and/or physical examination subject who has positive sars-cov-2 igg ab results during screening visit (visit 1) subject previously diagnosed with covid-19 subject with any acute, chronic, or clinically significant disease as a result of physical examination or laboratory examination at the screening visit (visit 1) subject with a history of malignancy within 5 years before the first dose of the investigational drug (except for basal cell and squamous cell carcinoma of the skin) subject with immune dysfunction including immunodeficiency disease through medical history and/or physical examination, or with a family history subject with a positive result of virus test (hepatitis b test, hepatitis a test, human immunodeficiency virus test, hepatitis c test) at the screening visit (visit 1) subject who are significantly abnormal clinically in laboratory tests, electrocardiogram, chest, and x-rays performed at the screening visit (visit 1) and those who are judged impossible to participate in the clinical trial at the discretion of the investigator subject with a history of hypersensitivity or severe allergic reaction to vaccine administration [e.g. anaphylaxis, guillain-barre syndrome, urticaria*, other clinically significant reactions requiring medical intervention] urticaria: those with a history of systemic urticaria within 5 years before administration of investigational drugs subject with diseases on such systems as hepatobiliary, kidney, nervous system (central or peripheral), respiratory (asthma, pneumonia, etc.), endocrine (uncontrolled diabetes mellitus, hyperlipidemia, etc.), cardiovascular (congestive heart failure, coronary artery disease, myocardial infarction, uncontrolled hypertension) etc.), urinary, psychiatric, musculoskeletal disorders or have a clinically significant history that it is judged to be unable to participate in a clinical trial under the judgment of the investigator subject with autoimmune diseases including autoimmune hypothyroidism and psoriasis subject with suspected or history of alcohol or substance abuse 12 months prior to the scheduled screening visit (visit 1). alcohol abuse standards are defined as follows: subject who has had a serious adverse reaction to a drug containing the same component as the investigational drug or has a history of allergy subject who has had a cough, dyspnea, chills, muscle pain, headache, sore throat, loss of smell or taste and an acute fever in which the body temperature exceeds 37.5°c within 72 hours prior to administration of the clinical trial drug subject who has been diagnosed with covid-19 and/or have been confirmed or treated for covid-19 infection as a result of laboratory tests subject with a history of previous mers-cov or sars-cov infection subject with a history of hereditary or idiopathic angioneurotic edema subject with a history of organ or bone marrow transplantation [relating to contraindicated drugs] subject who has experience in administering an immunosuppressant or immune modifying drug within 6 months prior to administration of an investigational drug patients with hemophilia who are at risk of serious bleeding when injected intramuscularly or are taking anticoagulants. subject who has received immunoglobulin or blood-derived products within 3 months prior to administration of the investigational drug or are expected to administer it during the clinical trial period subject who participated in other clinical trials similar to the investigational drug before the screening visit (visit 1) subject with a history of mers-cov or sars-cov vaccination subject who haa received or plan to administer the vaccine within 4 weeks before/after administration of this investigational drug subject with a history of platelet-related disease or hemorrhagic disease, a history of severe bleeding or bruising after intramuscular injection or venipuncture or a person taking anticoagulants if there is a history of dependent administration of psychotropic drugs or narcotic analgesics within 6 months prior to administration of the investigational drug or in case of a mental illness or social condition in which it is difficult to comply with the clinical trial procedure according to the judgment of the investigator