inclusion criteria: * male ≥ 18 years of age and female ≥ 55 years of age * diagnosis of positive sars-cov-2 infection confirmed by clinical diagnosis and / or rt-pcr test * hospitalized patients in acute disease\* stages of the disease * agree to participate in the study prior to signing an informed consent. * patients with conventional treatment with anticoagulants (noxaparin) * acute disease: patients who are hospitalized, conscious, not intubated, with biochemical values of d-dimer\> 2, ferritin\> 1000 u.

inclusion criteria: * male ≥ 18 years of age and female ≥ 55 years of age * diagnosis of positive sars-cov-2 infection confirmed by clinical diagnosis and / or rt-pcr test * hospitalized patients in acute disease\* stages of the disease * agree to participate in the study prior to signing an informed consent. * patients with conventional treatment with anticoagulants (noxaparin) * acute disease: patients who are hospitalized, conscious, not intubated, with biochemical values of d-dimer\> 2, ferritin\> 1000 u.

inclusion criteria: - male ≥ 18 years of age and female ≥ 55 years of age - diagnosis of positive sars-cov-2 infection confirmed by clinical diagnosis and / or rt-pcr test - hospitalized patients in acute disease* stages of the disease - agree to participate in the study prior to signing an informed consent. - patients with conventional treatment with anticoagulants (noxaparin) - acute disease: patients who are hospitalized, conscious, not intubated, with biochemical values of d-dimer> 2, ferritin> 1000 u.

inclusion criteria: - male ≥ 18 years of age and female ≥ 55 years of age - diagnosis of positive sars-cov-2 infection confirmed by clinical diagnosis and / or rt-pcr test - hospitalized patients in acute disease* stages of the disease - agree to participate in the study prior to signing an informed consent. - patients with conventional treatment with anticoagulants (noxaparin) - acute disease: patients who are hospitalized, conscious, not intubated, with biochemical values of d-dimer> 2, ferritin> 1000 u.