* patients with abnormal genital bleeding * patients with protein c or protein s deficiency * patients with liver failure (cirrhosis, hepatitis c) * patients with history of allergic reaction to estrogens use * patients receiving lamotrigine therapy * patients with a history of breast cancer and / or endometrial cancer * patients with severe hypoxia at risk of acute intubation in ed * patients with a history of cerebrovascular history * male patients with testosterone treatment * patients with a history of myocardial infarction, who have cardiac stents and / or unstable angina pectoris * patients with previous hormonal treatment

* patients with abnormal genital bleeding * patients with protein c or protein s deficiency * patients with liver failure (cirrhosis, hepatitis c) * patients with history of allergic reaction to estrogens use * patients receiving lamotrigine therapy * patients with a history of breast cancer and / or endometrial cancer * patients with severe hypoxia at risk of acute intubation in ed * patients with a history of cerebrovascular history * male patients with testosterone treatment * patients with a history of myocardial infarction, who have cardiac stents and / or unstable angina pectoris * patients with previous hormonal treatment

- patients with abnormal genital bleeding - patients with protein c or protein s deficiency - patients with liver failure (cirrhosis, hepatitis c) - patients with history of allergic reaction to estrogens use - patients receiving lamotrigine therapy - patients with a history of breast cancer and / or endometrial cancer - patients with severe hypoxia at risk of acute intubation in ed - patients with a history of cerebrovascular history - male patients with testosterone treatment - patients with a history of myocardial infarction, who have cardiac stents and / or unstable angina pectoris - patients with previous hormonal treatment

- patients with abnormal genital bleeding - patients with protein c or protein s deficiency - patients with liver failure (cirrhosis, hepatitis c) - patients with history of allergic reaction to estrogens use - patients receiving lamotrigine therapy - patients with a history of breast cancer and / or endometrial cancer - patients with severe hypoxia at risk of acute intubation in ed - patients with a history of cerebrovascular history - male patients with testosterone treatment - patients with a history of myocardial infarction, who have cardiac stents and / or unstable angina pectoris - patients with previous hormonal treatment