inclusion criteria: * covid-19 infection diagnosed * risk factors for the development of an ards according to an adapted eali (early acute lung injury score) ≥ 2 points (with at least one point from the eali score) eali score: * 2-6l o2 supplementation to achieve a sao2\>90%: 1 point * \>6l o2 supplementation to achieve a sao2\>90%: 2 points * respiratory rate ≥ 30/min: 1 point * immunosuppression: 1 point modification (for adapting for risk factors for ards in sars-cov-2 affected patients * arterial hypertension: 1 point * diabetes: 1 point * fever \> 39°c: 1 point * age \> 18 years * ability to adequate compliance with the inhalation manoeuvre * ability to sign the informed consent

inclusion criteria: * covid-19 infection diagnosed * risk factors for the development of an ards according to an adapted eali (early acute lung injury score) ≥ 2 points (with at least one point from the eali score) eali score: * 2-6l o2 supplementation to achieve a sao2\>90%: 1 point * \>6l o2 supplementation to achieve a sao2\>90%: 2 points * respiratory rate ≥ 30/min: 1 point * immunosuppression: 1 point modification (for adapting for risk factors for ards in sars-cov-2 affected patients * arterial hypertension: 1 point * diabetes: 1 point * fever \> 39°c: 1 point * age \> 18 years * ability to adequate compliance with the inhalation manoeuvre * ability to sign the informed consent

inclusion criteria: - covid-19 infection diagnosed - risk factors for the development of an ards according to an adapted eali (early acute lung injury score) ≥ 2 points (with at least one point from the eali score) eali score: - 2-6l o2 supplementation to achieve a sao2>90%: 1 point - >6l o2 supplementation to achieve a sao2>90%: 2 points - respiratory rate ≥ 30/min: 1 point - immunosuppression: 1 point modification (for adapting for risk factors for ards in sars-cov-2 affected patients - arterial hypertension: 1 point - diabetes: 1 point - fever > 39°c: 1 point - age > 18 years - ability to adequate compliance with the inhalation manoeuvre - ability to sign the informed consent

inclusion criteria: - covid-19 infection diagnosed - risk factors for the development of an ards according to an adapted eali (early acute lung injury score) ≥ 2 points (with at least one point from the eali score) eali score: - 2-6l o2 supplementation to achieve a sao2>90%: 1 point - >6l o2 supplementation to achieve a sao2>90%: 2 points - respiratory rate ≥ 30/min: 1 point - immunosuppression: 1 point modification (for adapting for risk factors for ards in sars-cov-2 affected patients - arterial hypertension: 1 point - diabetes: 1 point - fever > 39°c: 1 point - age > 18 years - ability to adequate compliance with the inhalation manoeuvre - ability to sign the informed consent