* inclusion criteria: 1. male or female participants between the ages of 18 and 79 years. 2. confirmed sars-cov-2 infection. 3. hospitalized for covid-19. 4. symptoms consistent with covid-19 indicated by at least 1 of the following: fever, cough, sore throat, malaise, headache, muscle pain, shortness of breath, new loss of taste and smell, nausea, chills, fatigue, rhinorrhea, diarrhea, vomiting or radiographic infiltrates by imaging consistent with covid-19 5. total body weight \>=50 kg (110 lb), bmi \<40 kg/m2; bmi \<35 kg/m2 for 76- 79 years. *

* inclusion criteria: 1. male or female participants between the ages of 18 and 79 years. 2. confirmed sars-cov-2 infection. 3. hospitalized for covid-19. 4. symptoms consistent with covid-19 indicated by at least 1 of the following: fever, cough, sore throat, malaise, headache, muscle pain, shortness of breath, new loss of taste and smell, nausea, chills, fatigue, rhinorrhea, diarrhea, vomiting or radiographic infiltrates by imaging consistent with covid-19 5. total body weight \>=50 kg (110 lb), bmi \<40 kg/m2; bmi \<35 kg/m2 for 76- 79 years. *

inclusion criteria: male or female participants between the ages of 18 and 79 years. confirmed sars-cov-2 infection. hospitalized for covid-19. symptoms consistent with covid-19 indicated by at least 1 of the following: fever, cough, sore throat, malaise, headache, muscle pain, shortness of breath, new loss of taste and smell, nausea, chills, fatigue, rhinorrhea, diarrhea, vomiting or radiographic infiltrates by imaging consistent with covid-19 total body weight >=50 kg (110 lb), bmi <40 kg/m2; bmi <35 kg/m2 for 76- 79 years.

inclusion criteria: male or female participants between the ages of 18 and 79 years. confirmed sars-cov-2 infection. hospitalized for covid-19. symptoms consistent with covid-19 indicated by at least 1 of the following: fever, cough, sore throat, malaise, headache, muscle pain, shortness of breath, new loss of taste and smell, nausea, chills, fatigue, rhinorrhea, diarrhea, vomiting or radiographic infiltrates by imaging consistent with covid-19 total body weight >=50 kg (110 lb), bmi <40 kg/m2; bmi <35 kg/m2 for 76- 79 years.

- inclusion criteria: 1. male or female participants between the ages of 18 and 79 years. 2. confirmed sars-cov-2 infection. 3. hospitalized for covid-19. 4. symptoms consistent with covid-19 indicated by at least 1 of the following: fever, cough, sore throat, malaise, headache, muscle pain, shortness of breath, new loss of taste and smell, nausea, chills, fatigue, rhinorrhea, diarrhea, vomiting or radiographic infiltrates by imaging consistent with covid-19 5. total body weight >=50 kg (110 lb), bmi <40 kg/m2; bmi <35 kg/m2 for 76- 79 years. -

- inclusion criteria: 1. male or female participants between the ages of 18 and 79 years. 2. confirmed sars-cov-2 infection. 3. hospitalized for covid-19. 4. symptoms consistent with covid-19 indicated by at least 1 of the following: fever, cough, sore throat, malaise, headache, muscle pain, shortness of breath, new loss of taste and smell, nausea, chills, fatigue, rhinorrhea, diarrhea, vomiting or radiographic infiltrates by imaging consistent with covid-19 5. total body weight >=50 kg (110 lb), bmi <40 kg/m2; bmi <35 kg/m2 for 76- 79 years. -

- inclusion criteria: 1. male or female participants between the ages of 18 and 75 years. 2. confirmed sars-cov-2 infection as determined by standard rt- pcr assay. 3. hospitalized for covid-19, with mild or moderate disease (8-point ordinal scale categories 4 to 7). 4. symptoms consistent with mild or moderate covid-19 indicated by at least 1 of the following: fever, cough, sore throat, malaise, headache, muscle pain, gastrointestinal symptoms, shortness of breath (at rest or with exertion), or dyspnea. 5. total body weight >=50 kg (110 lb), bmi <35 kg/m2. -

- inclusion criteria: 1. male or female participants between the ages of 18 and 75 years. 2. confirmed sars-cov-2 infection as determined by standard rt- pcr assay. 3. hospitalized for covid-19, with mild or moderate disease (8-point ordinal scale categories 4 to 7). 4. symptoms consistent with mild or moderate covid-19 indicated by at least 1 of the following: fever, cough, sore throat, malaise, headache, muscle pain, gastrointestinal symptoms, shortness of breath (at rest or with exertion), or dyspnea. 5. total body weight >=50 kg (110 lb), bmi <35 kg/m2. -