1. positive results of sars-cov-2 rt-pcr within 24 hours; 2. the subject has a history of sars-cov-2 infection within 3 months; 3. the anti-sars-cov-2 igm antibody was positive during the screening period. 4. history of human coronavirus infection or disease with severe acute respiratory syndrome (sars), middle east respiratory syndrome (mers), etc.; 5. previous history of convulsion, epilepsy, encephalopathy or psychosis or family history; 6. needle fainter; 7. those who plan to become pregnant or donate sperm or eggs during the trial period (within 6 months after exemption); 8. previous history of allergic reaction or allergic reaction to any vaccine and its excipients, such as allergy, urticaria, severe eczema, dyspnea, laryngeal edema, angioneurotic edema, etc.; 9. received subunit or inactivated vaccine within 14 days or live attenuated vaccine within 1 month prior to receiving the experimental vaccine; 10. participating in any other interventional test device or drug study within 30 days prior to screening, or currently using another investigational drug or within 5 half-life after the last administration of the study drug; 11. a genetic tendency to hemorrhage or coagulation abnormalities (such as cytokine defects, coagulation disorders or platelet disorders), or a history of severe bleeding, or a history of excessive bleeding or ecchymosis following intramuscular injection or venipuncture; 12. confirmation of diseases affecting the functioning of the immune system, including cancer, congenital or acquired immunodeficiency (e.g., human immunodeficiency virus (hiv) infection), uncontrolled autoimmune diseases, based on known medical history or diagnosis; 13. there are serious or uncontrollable respiratory diseases, cardiovascular diseases, nervous system diseases, blood and lymphatic system diseases, liver and kidney diseases, metabolic and skeletal system diseases that affect the evaluation of the results of this study as determined by the researchers; 14. anplenia or functional anplenia; 15. long-term use (continuous use ≥14 days) of immunosuppressants or other immunomodulatory drugs (such as corticosteroids: prednisone or similar drugs) within the 6 months prior to the study vaccine, but topical use (such as ointment, eye drops, inhalants or nasal spray) is permitted, and the topical use shall not exceed the dosage recommended in the instructions or any systemic signs of exposure; 16. received immunoglobulin and/or blood products in the three months prior to receiving the study vaccine; 17. patients undergoing anti-tuberculosis treatment; 18. medical, psychological, social or other conditions that, in the investigator's judgment, are inconsistent with the protocol or affect the subject's signing of informed consent.

1. positive results of sars-cov-2 rt-pcr within 24 hours; 2. the subject has a history of sars-cov-2 infection within 3 months; 3. the anti-sars-cov-2 igm antibody was positive during the screening period. 4. history of human coronavirus infection or disease with severe acute respiratory syndrome (sars), middle east respiratory syndrome (mers), etc.; 5. previous history of convulsion, epilepsy, encephalopathy or psychosis or family history; 6. needle fainter; 7. those who plan to become pregnant or donate sperm or eggs during the trial period (within 6 months after exemption); 8. previous history of allergic reaction or allergic reaction to any vaccine and its excipients, such as allergy, urticaria, severe eczema, dyspnea, laryngeal edema, angioneurotic edema, etc.; 9. received subunit or inactivated vaccine within 14 days or live attenuated vaccine within 1 month prior to receiving the experimental vaccine; 10. participating in any other interventional test device or drug study within 30 days prior to screening, or currently using another investigational drug or within 5 half-life after the last administration of the study drug; 11. a genetic tendency to hemorrhage or coagulation abnormalities (such as cytokine defects, coagulation disorders or platelet disorders), or a history of severe bleeding, or a history of excessive bleeding or ecchymosis following intramuscular injection or venipuncture; 12. confirmation of diseases affecting the functioning of the immune system, including cancer, congenital or acquired immunodeficiency (e.g., human immunodeficiency virus (hiv) infection), uncontrolled autoimmune diseases, based on known medical history or diagnosis; 13. there are serious or uncontrollable respiratory diseases, cardiovascular diseases, nervous system diseases, blood and lymphatic system diseases, liver and kidney diseases, metabolic and skeletal system diseases that affect the evaluation of the results of this study as determined by the researchers; 14. anplenia or functional anplenia; 15. long-term use (continuous use ≥14 days) of immunosuppressants or other immunomodulatory drugs (such as corticosteroids: prednisone or similar drugs) within the 6 months prior to the study vaccine, but topical use (such as ointment, eye drops, inhalants or nasal spray) is permitted, and the topical use shall not exceed the dosage recommended in the instructions or any systemic signs of exposure; 16. received immunoglobulin and/or blood products in the three months prior to receiving the study vaccine; 17. patients undergoing anti-tuberculosis treatment; 18. medical, psychological, social or other conditions that, in the investigator's judgment, are inconsistent with the protocol or affect the subject's signing of informed consent.

positive results of sars-cov-2 rt-pcr within 24 hours; the subject has a history of sars-cov-2 infection within 3 months; the anti-sars-cov-2 igm antibody was positive during the screening period. history of human coronavirus infection or disease with severe acute respiratory syndrome (sars), middle east respiratory syndrome (mers), etc.; previous history of convulsion, epilepsy, encephalopathy or psychosis or family history; needle fainter; those who plan to become pregnant or donate sperm or eggs during the trial period (within 6 months after exemption); previous history of allergic reaction or allergic reaction to any vaccine and its excipients, such as allergy, urticaria, severe eczema, dyspnea, laryngeal edema, angioneurotic edema, etc.; received subunit or inactivated vaccine within 14 days or live attenuated vaccine within 1 month prior to receiving the experimental vaccine; participating in any other interventional test device or drug study within 30 days prior to screening, or currently using another investigational drug or within 5 half-life after the last administration of the study drug; a genetic tendency to hemorrhage or coagulation abnormalities (such as cytokine defects, coagulation disorders or platelet disorders), or a history of severe bleeding, or a history of excessive bleeding or ecchymosis following intramuscular injection or venipuncture; confirmation of diseases affecting the functioning of the immune system, including cancer, congenital or acquired immunodeficiency (e.g., human immunodeficiency virus (hiv) infection), uncontrolled autoimmune diseases, based on known medical history or diagnosis; there are serious or uncontrollable respiratory diseases, cardiovascular diseases, nervous system diseases, blood and lymphatic system diseases, liver and kidney diseases, metabolic and skeletal system diseases that affect the evaluation of the results of this study as determined by the researchers; anplenia or functional anplenia; long-term use (continuous use ≥14 days) of immunosuppressants or other immunomodulatory drugs (such as corticosteroids: prednisone or similar drugs) within the 6 months prior to the study vaccine, but topical use (such as ointment, eye drops, inhalants or nasal spray) is permitted, and the topical use shall not exceed the dosage recommended in the instructions or any systemic signs of exposure; received immunoglobulin and/or blood products in the three months prior to receiving the study vaccine; patients undergoing anti-tuberculosis treatment; medical, psychological, social or other conditions that, in the investigator's judgment, are inconsistent with the protocol or affect the subject's signing of informed consent.

positive results of sars-cov-2 rt-pcr within 24 hours; the subject has a history of sars-cov-2 infection within 3 months; the anti-sars-cov-2 igm antibody was positive during the screening period. history of human coronavirus infection or disease with severe acute respiratory syndrome (sars), middle east respiratory syndrome (mers), etc.; previous history of convulsion, epilepsy, encephalopathy or psychosis or family history; needle fainter; those who plan to become pregnant or donate sperm or eggs during the trial period (within 6 months after exemption); previous history of allergic reaction or allergic reaction to any vaccine and its excipients, such as allergy, urticaria, severe eczema, dyspnea, laryngeal edema, angioneurotic edema, etc.; received subunit or inactivated vaccine within 14 days or live attenuated vaccine within 1 month prior to receiving the experimental vaccine; participating in any other interventional test device or drug study within 30 days prior to screening, or currently using another investigational drug or within 5 half-life after the last administration of the study drug; a genetic tendency to hemorrhage or coagulation abnormalities (such as cytokine defects, coagulation disorders or platelet disorders), or a history of severe bleeding, or a history of excessive bleeding or ecchymosis following intramuscular injection or venipuncture; confirmation of diseases affecting the functioning of the immune system, including cancer, congenital or acquired immunodeficiency (e.g., human immunodeficiency virus (hiv) infection), uncontrolled autoimmune diseases, based on known medical history or diagnosis; there are serious or uncontrollable respiratory diseases, cardiovascular diseases, nervous system diseases, blood and lymphatic system diseases, liver and kidney diseases, metabolic and skeletal system diseases that affect the evaluation of the results of this study as determined by the researchers; anplenia or functional anplenia; long-term use (continuous use ≥14 days) of immunosuppressants or other immunomodulatory drugs (such as corticosteroids: prednisone or similar drugs) within the 6 months prior to the study vaccine, but topical use (such as ointment, eye drops, inhalants or nasal spray) is permitted, and the topical use shall not exceed the dosage recommended in the instructions or any systemic signs of exposure; received immunoglobulin and/or blood products in the three months prior to receiving the study vaccine; patients undergoing anti-tuberculosis treatment; medical, psychological, social or other conditions that, in the investigator's judgment, are inconsistent with the protocol or affect the subject's signing of informed consent.