inclusion criteria: 1. adults (age 18 years or older). 2. diagnosed with covid-19 according to the diagnosis and clinical management of covid-19. (trial version 10). 3. severe and critical ill patients with covid-19. 4. patients who voluntarily participate in the study and sign the informed consent form.

inclusion criteria: 1. adults (age 18 years or older). 2. diagnosed with covid-19 according to the diagnosis and clinical management of covid-19. (trial version 10). 3. severe and critical ill patients with covid-19. 4. patients who voluntarily participate in the study and sign the informed consent form.

inclusion criteria: adults (age 18 years or older). diagnosed with covid-19 according to the diagnosis and clinical management of covid-19. (trial version 10). severe and critical ill patients with covid-19. patients who voluntarily participate in the study and sign the informed consent form.

inclusion criteria: adults (age 18 years or older). diagnosed with covid-19 according to the diagnosis and clinical management of covid-19. (trial version 10). severe and critical ill patients with covid-19. patients who voluntarily participate in the study and sign the informed consent form.