* contraindications to the class of drugs under study (c1 esterase inhibitor); * history or suspicion of allergy to rabbits; * women who are of childbearing potential and not using methods of contraception during the entire study period; * pregnant or breastfeeding females or has a positive serum β-human chorionic gonadotropin (hcg) pregnancy test at screening; * chronic liver disease (any child-pugh score b or c); * currently admitted to an icu or expected admission within the next 24 hours; and * currently receiving invasive or non-invasive ventilation

* contraindications to the class of drugs under study (c1 esterase inhibitor); * history or suspicion of allergy to rabbits; * women who are of childbearing potential and not using methods of contraception during the entire study period; * pregnant or breastfeeding females or has a positive serum β-human chorionic gonadotropin (hcg) pregnancy test at screening; * chronic liver disease (any child-pugh score b or c); * currently admitted to an icu or expected admission within the next 24 hours; and * currently receiving invasive or non-invasive ventilation

- contraindications to the class of drugs under study (c1 esterase inhibitor); - history or suspicion of allergy to rabbits; - women who are of childbearing potential and not using methods of contraception during the entire study period; - pregnant or breastfeeding females or has a positive serum β-human chorionic gonadotropin (hcg) pregnancy test at screening; - chronic liver disease (any child-pugh score b or c); - currently admitted to an icu or expected admission within the next 24 hours; and - currently receiving invasive or non-invasive ventilation

- contraindications to the class of drugs under study (c1 esterase inhibitor); - history or suspicion of allergy to rabbits; - women who are of childbearing potential and not using methods of contraception during the entire study period; - pregnant or breastfeeding females or has a positive serum β-human chorionic gonadotropin (hcg) pregnancy test at screening; - chronic liver disease (any child-pugh score b or c); - currently admitted to an icu or expected admission within the next 24 hours; and - currently receiving invasive or non-invasive ventilation