* patients who are currently or are expected to potentially progress to severe/critical covid-19 within 48 h of randomization; * patients with chronic respiratory diseases, including bronchial asthma and chronic obstructive pulmonary disease etc. * known history of moderate-severe liver impairment (e.g., child-pugh grade b or c, alanine aminotransferase (alt) and/or aspartate aminotransferase (ast) \> 5x upper limit normal (uln) , or acute liver failure within 6 months prior to screening;. * known history of severe renal impairment (e.g., chronic kidney disease-improved prediction equations(ckd-epi)formula based on serum creatinine, estimated glomerular filtration rate (egfr) \< 30 ml/min/1.73m2), or was receiving renal replacement therapy, such as peritoneal dialysis or hemodialysis, within 6 months prior to screening; * impaired immune system (including patients treated with systemic corticosteroids or other immunosuppressive agents, or cancer progression or recurrence) * suspected or confirmed concurrent active systemic infections other than covid-19 that may interfere with the assessment of response to study interventions. * need for radiotherapy, chemotherapy, emergency surgery or surgical treatment at screening, or other emergencies (e.g. acute coronary syndrome, acute pulmonary embolism, etc.). * patients with a history of cardiopulmonary resuscitation or major surgery within 30 days prior to randomization, and patients with other potentially life-threatening clinical conditions or other emergencies. * history of hypersensitivity or other contraindications to any component of the study intervention. * patients who received or expected to receive anti-sars-cov-2 viral drugs (e.g., nirmatrelvir/ritonavir, molnupiravir, etc.) within 14 days prior to randomization. * have received (within 30 days prior to randomization or within 5 half-lives, whichever is longer) or expect to receive covid-19 monoclonal antibody or recovery covid-19 plasma therapy. * any sars-cov-2 vaccination within 3 months prior to randomization. * within 28 days or 5 half-lives (whichever is longer) prior to randomization or in clinical studies with other investigational drugs or devices, including studies for covid-19. * mental illnesses that, in the judgment of the investigator, are not appropriate for participation in this study. * any other situation that the investigator believes may affect the subject's informed consent or adherence to the protocol, or the subject's participation in the study may affect the outcome of the study or his or her own safety, in the investigator's judgment.

* patients who are currently or are expected to potentially progress to severe/critical covid-19 within 48 h of randomization; * patients with chronic respiratory diseases, including bronchial asthma and chronic obstructive pulmonary disease etc. * known history of moderate-severe liver impairment (e.g., child-pugh grade b or c, alanine aminotransferase (alt) and/or aspartate aminotransferase (ast) \> 5x upper limit normal (uln) , or acute liver failure within 6 months prior to screening;. * known history of severe renal impairment (e.g., chronic kidney disease-improved prediction equations(ckd-epi)formula based on serum creatinine, estimated glomerular filtration rate (egfr) \< 30 ml/min/1.73m2), or was receiving renal replacement therapy, such as peritoneal dialysis or hemodialysis, within 6 months prior to screening; * impaired immune system (including patients treated with systemic corticosteroids or other immunosuppressive agents, or cancer progression or recurrence) * suspected or confirmed concurrent active systemic infections other than covid-19 that may interfere with the assessment of response to study interventions. * need for radiotherapy, chemotherapy, emergency surgery or surgical treatment at screening, or other emergencies (e.g. acute coronary syndrome, acute pulmonary embolism, etc.). * patients with a history of cardiopulmonary resuscitation or major surgery within 30 days prior to randomization, and patients with other potentially life-threatening clinical conditions or other emergencies. * history of hypersensitivity or other contraindications to any component of the study intervention. * patients who received or expected to receive anti-sars-cov-2 viral drugs (e.g., nirmatrelvir/ritonavir, molnupiravir, etc.) within 14 days prior to randomization. * have received (within 30 days prior to randomization or within 5 half-lives, whichever is longer) or expect to receive covid-19 monoclonal antibody or recovery covid-19 plasma therapy. * any sars-cov-2 vaccination within 3 months prior to randomization. * within 28 days or 5 half-lives (whichever is longer) prior to randomization or in clinical studies with other investigational drugs or devices, including studies for covid-19. * mental illnesses that, in the judgment of the investigator, are not appropriate for participation in this study. * any other situation that the investigator believes may affect the subject's informed consent or adherence to the protocol, or the subject's participation in the study may affect the outcome of the study or his or her own safety, in the investigator's judgment.

patients who are currently or are expected to potentially progress to severe/critical covid-19 within 48 h of randomization; patients with chronic respiratory diseases, including bronchial asthma and chronic obstructive pulmonary disease etc. known history of moderate-severe liver impairment (e.g., child-pugh grade b or c, alanine aminotransferase (alt) and/or aspartate aminotransferase (ast) > 5x upper limit normal (uln) , or acute liver failure within 6 months prior to screening;. known history of severe renal impairment (e.g., chronic kidney disease-improved prediction equations(ckd-epi)formula based on serum creatinine, estimated glomerular filtration rate (egfr) < 30 ml/min/1.73m2), or was receiving renal replacement therapy, such as peritoneal dialysis or hemodialysis, within 6 months prior to screening; impaired immune system (including patients treated with systemic corticosteroids or other immunosuppressive agents, or cancer progression or recurrence) suspected or confirmed concurrent active systemic infections other than covid-19 that may interfere with the assessment of response to study interventions. need for radiotherapy, chemotherapy, emergency surgery or surgical treatment at screening, or other emergencies (e.g. acute coronary syndrome, acute pulmonary embolism, etc.). patients with a history of cardiopulmonary resuscitation or major surgery within 30 days prior to randomization, and patients with other potentially life-threatening clinical conditions or other emergencies. history of hypersensitivity or other contraindications to any component of the study intervention. patients who received or expected to receive anti-sars-cov-2 viral drugs (e.g., nirmatrelvir/ritonavir, molnupiravir, etc.) within 14 days prior to randomization. have received (within 30 days prior to randomization or within 5 half-lives, whichever is longer) or expect to receive covid-19 monoclonal antibody or recovery covid-19 plasma therapy. any sars-cov-2 vaccination within 3 months prior to randomization. within 28 days or 5 half-lives (whichever is longer) prior to randomization or in clinical studies with other investigational drugs or devices, including studies for covid-19. mental illnesses that, in the judgment of the investigator, are not appropriate for participation in this study. any other situation that the investigator believes may affect the subject's informed consent or adherence to the protocol, or the subject's participation in the study may affect the outcome of the study or his or her own safety, in the investigator's judgment.

patients who are currently or are expected to potentially progress to severe/critical covid-19 within 48 h of randomization; patients with chronic respiratory diseases, including bronchial asthma and chronic obstructive pulmonary disease etc. known history of moderate-severe liver impairment (e.g., child-pugh grade b or c, alanine aminotransferase (alt) and/or aspartate aminotransferase (ast) > 5x upper limit normal (uln) , or acute liver failure within 6 months prior to screening;. known history of severe renal impairment (e.g., chronic kidney disease-improved prediction equations(ckd-epi)formula based on serum creatinine, estimated glomerular filtration rate (egfr) < 30 ml/min/1.73m2), or was receiving renal replacement therapy, such as peritoneal dialysis or hemodialysis, within 6 months prior to screening; impaired immune system (including patients treated with systemic corticosteroids or other immunosuppressive agents, or cancer progression or recurrence) suspected or confirmed concurrent active systemic infections other than covid-19 that may interfere with the assessment of response to study interventions. need for radiotherapy, chemotherapy, emergency surgery or surgical treatment at screening, or other emergencies (e.g. acute coronary syndrome, acute pulmonary embolism, etc.). patients with a history of cardiopulmonary resuscitation or major surgery within 30 days prior to randomization, and patients with other potentially life-threatening clinical conditions or other emergencies. history of hypersensitivity or other contraindications to any component of the study intervention. patients who received or expected to receive anti-sars-cov-2 viral drugs (e.g., nirmatrelvir/ritonavir, molnupiravir, etc.) within 14 days prior to randomization. have received (within 30 days prior to randomization or within 5 half-lives, whichever is longer) or expect to receive covid-19 monoclonal antibody or recovery covid-19 plasma therapy. any sars-cov-2 vaccination within 3 months prior to randomization. within 28 days or 5 half-lives (whichever is longer) prior to randomization or in clinical studies with other investigational drugs or devices, including studies for covid-19. mental illnesses that, in the judgment of the investigator, are not appropriate for participation in this study. any other situation that the investigator believes may affect the subject's informed consent or adherence to the protocol, or the subject's participation in the study may affect the outcome of the study or his or her own safety, in the investigator's judgment.