inclusion criteria: * age at the time of first dose of vaccine: adults aged 18-59 years (including boundary values), elderly ≥60 years, both sexes; * armpit temperature \<37.3℃ on the day of enrollment; * based on the medical history and relevant physical examination and laboratory examination results, the investigator clinically determined that the patient was in good health; * subjects have independent judgment ability, can read, understand and complete vaccination diary cards, and they participate voluntarily and sign an informed consent form.

inclusion criteria: * age at the time of first dose of vaccine: adults aged 18-59 years (including boundary values), elderly ≥60 years, both sexes; * armpit temperature \<37.3℃ on the day of enrollment; * based on the medical history and relevant physical examination and laboratory examination results, the investigator clinically determined that the patient was in good health; * subjects have independent judgment ability, can read, understand and complete vaccination diary cards, and they participate voluntarily and sign an informed consent form.

inclusion criteria: age at the time of first dose of vaccine: adults aged 18-59 years (including boundary values), elderly ≥60 years, both sexes; armpit temperature <37.3℃ on the day of enrollment; based on the medical history and relevant physical examination and laboratory examination results, the investigator clinically determined that the patient was in good health; subjects have independent judgment ability, can read, understand and complete vaccination diary cards, and they participate voluntarily and sign an informed consent form.

inclusion criteria: age at the time of first dose of vaccine: adults aged 18-59 years (including boundary values), elderly ≥60 years, both sexes; armpit temperature <37.3℃ on the day of enrollment; based on the medical history and relevant physical examination and laboratory examination results, the investigator clinically determined that the patient was in good health; subjects have independent judgment ability, can read, understand and complete vaccination diary cards, and they participate voluntarily and sign an informed consent form.