key inclusion criteria * outpatient with a rt-qpcr confirmation of sars-cov-2 infection * body mass index (bmi) at screening of 18.0 - 34.9 kg/m\^2 * presence of at least one symptom consistent with covid-19 * mild illness as defined by no requirement of supplementary oxygen or hospitalization criteria are met key exclusion criteria * presence of a risk factor for disease progression documented for covid-19 such as: uncontrolled diabetes, uncontrolled hypertension, cardiovascular disease, pulmonary disease, copd, asthma, active cancer, immunosuppression, hypercoagulable states, ckd currently under dialysis * documented allergy to equine serum proteins * previous hospitalization due to covid-19 * supplementary oxygen, invasive ventilation, or mechanical circulatory support requirements * having received convalescent plasma or intravenous immunoglobulins for the treatment of covid-19 * previous vaccination or plans to get vaccinated for covid-19 * in the opinion of investigator, other health conditions that suppose an increased risk of progression of disease note: other inclusion/exclusion criteria apply

key inclusion criteria * outpatient with a rt-qpcr confirmation of sars-cov-2 infection * body mass index (bmi) at screening of 18.0 - 34.9 kg/m\^2 * presence of at least one symptom consistent with covid-19 * mild illness as defined by no requirement of supplementary oxygen or hospitalization criteria are met key exclusion criteria * presence of a risk factor for disease progression documented for covid-19 such as: uncontrolled diabetes, uncontrolled hypertension, cardiovascular disease, pulmonary disease, copd, asthma, active cancer, immunosuppression, hypercoagulable states, ckd currently under dialysis * documented allergy to equine serum proteins * previous hospitalization due to covid-19 * supplementary oxygen, invasive ventilation, or mechanical circulatory support requirements * having received convalescent plasma or intravenous immunoglobulins for the treatment of covid-19 * previous vaccination or plans to get vaccinated for covid-19 * in the opinion of investigator, other health conditions that suppose an increased risk of progression of disease note: other inclusion/exclusion criteria apply

key inclusion criteria - outpatient with a rt-qpcr confirmation of sars-cov-2 infection - body mass index (bmi) at screening of 18.0 - 34.9 kg/m^2 - presence of at least one symptom consistent with covid-19 - mild illness as defined by no requirement of supplementary oxygen or hospitalization criteria are met key exclusion criteria - presence of a risk factor for disease progression documented for covid-19 such as: uncontrolled diabetes, uncontrolled hypertension, cardiovascular disease, pulmonary disease, copd, asthma, active cancer, immunosuppression, hypercoagulable states, ckd currently under dialysis - documented allergy to equine serum proteins - previous hospitalization due to covid-19 - supplementary oxygen, invasive ventilation, or mechanical circulatory support requirements - having received convalescent plasma or intravenous immunoglobulins for the treatment of covid-19 - previous vaccination or plans to get vaccinated for covid-19 - in the opinion of investigator, other health conditions that suppose an increased risk of progression of disease note: other inclusion/exclusion criteria apply

key inclusion criteria - outpatient with a rt-qpcr confirmation of sars-cov-2 infection - body mass index (bmi) at screening of 18.0 - 34.9 kg/m^2 - presence of at least one symptom consistent with covid-19 - mild illness as defined by no requirement of supplementary oxygen or hospitalization criteria are met key exclusion criteria - presence of a risk factor for disease progression documented for covid-19 such as: uncontrolled diabetes, uncontrolled hypertension, cardiovascular disease, pulmonary disease, copd, asthma, active cancer, immunosuppression, hypercoagulable states, ckd currently under dialysis - documented allergy to equine serum proteins - previous hospitalization due to covid-19 - supplementary oxygen, invasive ventilation, or mechanical circulatory support requirements - having received convalescent plasma or intravenous immunoglobulins for the treatment of covid-19 - previous vaccination or plans to get vaccinated for covid-19 - in the opinion of investigator, other health conditions that suppose an increased risk of progression of disease note: other inclusion/exclusion criteria apply

inclusion criteria: - subjects of both sexes aged ≥ 18 years - patients with a confirmed infection with sars-cov-2 by pcr - patients admitted for hospitalization for covid-19 disease that fulfills any of the following: 1. clinical or imaging evidence of pneumonia defined as: spo2 < 94% or pao2/fio2 (spo2/fio2) < 300 or chest imaging consistent with pneumonia or clinical evidence of pneumonia (fever, cough, dyspnea and respiratory frequency > 24 respirations/min) or 2. score of 4 (hospitalized no oxygen requirement, requires medical care), 5 (hospitalized, low-flow oxygen requirement) or 6 (hospitalized, high-flow oxygen or non-invasive mechanical ventilation requirement) in the niaid 8-point ordinal scale of clinical status for covid-19 3. high risk markers of disease progression (at least on serum inflammatory marker elevated: c reactive protein, d-dimer, lactate dehydrogenase, ferritin) - agrees to participate in the study and signs written informed consent (signed by relative if applicable)

inclusion criteria: - subjects of both sexes aged ≥ 18 years - patients with a confirmed infection with sars-cov-2 by pcr - patients admitted for hospitalization for covid-19 disease that fulfills any of the following: 1. clinical or imaging evidence of pneumonia defined as: spo2 < 94% or pao2/fio2 (spo2/fio2) < 300 or chest imaging consistent with pneumonia or clinical evidence of pneumonia (fever, cough, dyspnea and respiratory frequency > 24 respirations/min) or 2. score of 4 (hospitalized no oxygen requirement, requires medical care), 5 (hospitalized, low-flow oxygen requirement) or 6 (hospitalized, high-flow oxygen or non-invasive mechanical ventilation requirement) in the niaid 8-point ordinal scale of clinical status for covid-19 3. high risk markers of disease progression (at least on serum inflammatory marker elevated: c reactive protein, d-dimer, lactate dehydrogenase, ferritin) - agrees to participate in the study and signs written informed consent (signed by relative if applicable)