inclusion criteria: 1. able and willing to provide written or electronic informed consent prior to any study-specific procedure. 2. age ≥50 at the time of signing the informed consent form. 3. women of reproductive potential must have a negative pregnancy test at screening and be using a highly effective method of contraception. highly effective methods of contraception 4. a male participant must wear a condom when engaging in any activity that allows for passage of ejaculate to another while taking the investigational product. male participants should also be advised of the benefit for a female partner to use a highly effective method of contraception as condom may break or leak. 5. self-reported symptoms of covid-19 with onset no more than five days prior to screening informed consent including at least one of, fever or chills, cough, sore throat, rhinorrhoea or rhinitis or sinusitis, shortness of breath, headache, myalgia, new onset anosmia or ageusia, nausea, diarrhoea, or extreme fatigue, or other symptoms recognized in local and international guidelines as typical of mild covid-19. 6. sars-cov-2 infection confirmed through a positive lumiradx rapid antigen test on the day of screening or a positive rt-pcr within two days prior to screening. 7. participant is at high risk for progression to severe covid-19, this defined as either: 1. age ≥50 with at least one of the following background or medical conditions: diabetes mellitus, obesity (bmi 30 kg/m2), hypertension, hiv, active or previous tb. 2. age ≥65 8. participant agrees to comply with study procedures, including the completion of a daily diary for 10 days from the time of enrolment, and to be available for study contacts and visits. -

inclusion criteria: 1. able and willing to provide written or electronic informed consent prior to any study-specific procedure. 2. age ≥50 at the time of signing the informed consent form. 3. women of reproductive potential must have a negative pregnancy test at screening and be using a highly effective method of contraception. highly effective methods of contraception 4. a male participant must wear a condom when engaging in any activity that allows for passage of ejaculate to another while taking the investigational product. male participants should also be advised of the benefit for a female partner to use a highly effective method of contraception as condom may break or leak. 5. self-reported symptoms of covid-19 with onset no more than five days prior to screening informed consent including at least one of, fever or chills, cough, sore throat, rhinorrhoea or rhinitis or sinusitis, shortness of breath, headache, myalgia, new onset anosmia or ageusia, nausea, diarrhoea, or extreme fatigue, or other symptoms recognized in local and international guidelines as typical of mild covid-19. 6. sars-cov-2 infection confirmed through a positive lumiradx rapid antigen test on the day of screening or a positive rt-pcr within two days prior to screening. 7. participant is at high risk for progression to severe covid-19, this defined as either: 1. age ≥50 with at least one of the following background or medical conditions: diabetes mellitus, obesity (bmi 30 kg/m2), hypertension, hiv, active or previous tb. 2. age ≥65 8. participant agrees to comply with study procedures, including the completion of a daily diary for 10 days from the time of enrolment, and to be available for study contacts and visits. -

inclusion criteria: able and willing to provide written or electronic informed consent prior to any study-specific procedure. age ≥50 at the time of signing the informed consent form. women of reproductive potential must have a negative pregnancy test at screening and be using a highly effective method of contraception. highly effective methods of contraception a male participant must wear a condom when engaging in any activity that allows for passage of ejaculate to another while taking the investigational product. male participants should also be advised of the benefit for a female partner to use a highly effective method of contraception as condom may break or leak. self-reported symptoms of covid-19 with onset no more than five days prior to screening informed consent including at least one of, fever or chills, cough, sore throat, rhinorrhoea or rhinitis or sinusitis, shortness of breath, headache, myalgia, new onset anosmia or ageusia, nausea, diarrhoea, or extreme fatigue, or other symptoms recognized in local and international guidelines as typical of mild covid-19. sars-cov-2 infection confirmed through a positive lumiradx rapid antigen test on the day of screening or a positive rt-pcr within two days prior to screening. participant is at high risk for progression to severe covid-19, this defined as either: age ≥50 with at least one of the following background or medical conditions: diabetes mellitus, obesity (bmi 30 kg/m2), hypertension, hiv, active or previous tb. age ≥65 participant agrees to comply with study procedures, including the completion of a daily diary for 10 days from the time of enrolment, and to be available for study contacts and visits. -

inclusion criteria: able and willing to provide written or electronic informed consent prior to any study-specific procedure. age ≥50 at the time of signing the informed consent form. women of reproductive potential must have a negative pregnancy test at screening and be using a highly effective method of contraception. highly effective methods of contraception a male participant must wear a condom when engaging in any activity that allows for passage of ejaculate to another while taking the investigational product. male participants should also be advised of the benefit for a female partner to use a highly effective method of contraception as condom may break or leak. self-reported symptoms of covid-19 with onset no more than five days prior to screening informed consent including at least one of, fever or chills, cough, sore throat, rhinorrhoea or rhinitis or sinusitis, shortness of breath, headache, myalgia, new onset anosmia or ageusia, nausea, diarrhoea, or extreme fatigue, or other symptoms recognized in local and international guidelines as typical of mild covid-19. sars-cov-2 infection confirmed through a positive lumiradx rapid antigen test on the day of screening or a positive rt-pcr within two days prior to screening. participant is at high risk for progression to severe covid-19, this defined as either: age ≥50 with at least one of the following background or medical conditions: diabetes mellitus, obesity (bmi 30 kg/m2), hypertension, hiv, active or previous tb. age ≥65 participant agrees to comply with study procedures, including the completion of a daily diary for 10 days from the time of enrolment, and to be available for study contacts and visits. -